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Cell-cycle-gated feedback control mediates desensitization to interferon stimulation

Cells use molecular circuits to interpret and respond to extracellular cues, such as hormones and cytokines, which are often released in a temporally varying fashion. In this study, we combine microfluidics, time-lapse microscopy, and computational modeling to investigate how the type I interferon (...

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Detalles Bibliográficos
Autores principales:	Mudla, Anusorn, Jiang, Yanfei, Arimoto, Kei-ichiro, Xu, Bingxian, Rajesh, Adarsh, Ryan, Andy P, Wang, Wei, Daugherty, Matthew D, Zhang, Dong-Er, Hao, Nan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2020
Materias:	Computational and Systems Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7500952/ https://www.ncbi.nlm.nih.gov/pubmed/32945770 http://dx.doi.org/10.7554/eLife.58825

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