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Lentiviral gene therapy rescues p47(phox) chronic granulomatous disease and the ability to fight Salmonella infection in mice

Chronic granulomatous disease (CGD) is an inherited primary immunodeficiency disorder characterised by recurrent and often life-threatening infections and hyperinflammation. It is caused by defects of the phagocytic NADPH oxidase, a multicomponent enzyme system responsible for effective pathogen kil...

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Detalles Bibliográficos
Autores principales:	Schejtman, Andrea, Aragão-Filho, Walmir Cutrim, Clare, Simon, Zinicola, Marta, Weisser, Maren, Burns, Siobhan O., Booth, Claire, Gaspar, Hubert B., Thomas, David C., Condino-Neto, Antonio, Thrasher, Adrian J., Santilli, Giorgia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Brief Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7500983/ https://www.ncbi.nlm.nih.gov/pubmed/32533104 http://dx.doi.org/10.1038/s41434-020-0164-6

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