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Risk factors for peripheral arterial disease in elderly patients with Type-2 diabetes mellitus: A clinical study
OBJECTIVES: To determine risk factors for peripheral arterial disease (PAD) in elderly patients with Type-2 diabetes mellitus. METHODS: The elderly patients with Type-2 diabetes treated in the Central Hospital of Cangzhou were enrolled and divided into PAD group and non-PAD group between October 201...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Professional Medical Publications
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7501018/ https://www.ncbi.nlm.nih.gov/pubmed/32968406 http://dx.doi.org/10.12669/pjms.36.6.2906 |
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author | Shou, Zhang Zhao, Yongcai Zhang, Yan Li, Shaoqing |
author_facet | Shou, Zhang Zhao, Yongcai Zhang, Yan Li, Shaoqing |
author_sort | Shou, Zhang |
collection | PubMed |
description | OBJECTIVES: To determine risk factors for peripheral arterial disease (PAD) in elderly patients with Type-2 diabetes mellitus. METHODS: The elderly patients with Type-2 diabetes treated in the Central Hospital of Cangzhou were enrolled and divided into PAD group and non-PAD group between October 2016 and November 2019, The data of the patients including age, gender, body mass index, blood pressure, hemoglobin A1c, high-density lipoprotein-cholesterol, low-density lipoprotein-cholesterol, total cholesterol, triglyceride, white cell count, lymphocyte count, high-sensitivity C-reactive protein, uric acid as well as living habits and complications of Type-2 diabetes mellitus were recorded to determine the risk factors for PAD. RESULTS: One thousand four hundred seventy six (1476) patients were enrolled, in which 465 patients were included in group of PAD, and 1011 in non-PAD group. The univariate analysis revealed that the two groups significantly differed in age (p=0.003), course of T2DM (p=0.001), hypertension (p=0.006), smoking habits (p<0.001), hyperuricemia (p<0.01), high-sensitivity C-reactive protein (p<0.01), white cell count (p<0.001), lymphocyte count (p<0.001) and diabetic neuropathy (p<0.001). In the multivariate analysis, age (OR: 1.56, 95% CI: 1.21-1.89), smoking habit (OR: 1.37, 95% CI: 1.19-1.68), hypertension (OR: 1.44, 95% CI: 1.15-1.98), diabetic neuropathy (OR: 3.55, 95% CI: 2.14-4.29), high-sensitivity C-reactive protein (OR: 1.74, 95% CI: 1.39-2.61) and hyperuricemia (OR: 2.71, 95% CI: 1.66-3.87) were significant risk factors for PAD. CONCLUSIONS: Age, smoking habit, hypertension, diabetic neuropathy, high-sensitivity C-reactive protein and hyperuricemia were independent risk factors for peripheral arterial disease in elderly patients with Type-2 diabetes mellitus. |
format | Online Article Text |
id | pubmed-7501018 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Professional Medical Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-75010182020-09-22 Risk factors for peripheral arterial disease in elderly patients with Type-2 diabetes mellitus: A clinical study Shou, Zhang Zhao, Yongcai Zhang, Yan Li, Shaoqing Pak J Med Sci Original Article OBJECTIVES: To determine risk factors for peripheral arterial disease (PAD) in elderly patients with Type-2 diabetes mellitus. METHODS: The elderly patients with Type-2 diabetes treated in the Central Hospital of Cangzhou were enrolled and divided into PAD group and non-PAD group between October 2016 and November 2019, The data of the patients including age, gender, body mass index, blood pressure, hemoglobin A1c, high-density lipoprotein-cholesterol, low-density lipoprotein-cholesterol, total cholesterol, triglyceride, white cell count, lymphocyte count, high-sensitivity C-reactive protein, uric acid as well as living habits and complications of Type-2 diabetes mellitus were recorded to determine the risk factors for PAD. RESULTS: One thousand four hundred seventy six (1476) patients were enrolled, in which 465 patients were included in group of PAD, and 1011 in non-PAD group. The univariate analysis revealed that the two groups significantly differed in age (p=0.003), course of T2DM (p=0.001), hypertension (p=0.006), smoking habits (p<0.001), hyperuricemia (p<0.01), high-sensitivity C-reactive protein (p<0.01), white cell count (p<0.001), lymphocyte count (p<0.001) and diabetic neuropathy (p<0.001). In the multivariate analysis, age (OR: 1.56, 95% CI: 1.21-1.89), smoking habit (OR: 1.37, 95% CI: 1.19-1.68), hypertension (OR: 1.44, 95% CI: 1.15-1.98), diabetic neuropathy (OR: 3.55, 95% CI: 2.14-4.29), high-sensitivity C-reactive protein (OR: 1.74, 95% CI: 1.39-2.61) and hyperuricemia (OR: 2.71, 95% CI: 1.66-3.87) were significant risk factors for PAD. CONCLUSIONS: Age, smoking habit, hypertension, diabetic neuropathy, high-sensitivity C-reactive protein and hyperuricemia were independent risk factors for peripheral arterial disease in elderly patients with Type-2 diabetes mellitus. Professional Medical Publications 2020 /pmc/articles/PMC7501018/ /pubmed/32968406 http://dx.doi.org/10.12669/pjms.36.6.2906 Text en Copyright: © Pakistan Journal of Medical Sciences http://creativecommons.org/licenses/by/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Shou, Zhang Zhao, Yongcai Zhang, Yan Li, Shaoqing Risk factors for peripheral arterial disease in elderly patients with Type-2 diabetes mellitus: A clinical study |
title | Risk factors for peripheral arterial disease in elderly patients with Type-2 diabetes mellitus: A clinical study |
title_full | Risk factors for peripheral arterial disease in elderly patients with Type-2 diabetes mellitus: A clinical study |
title_fullStr | Risk factors for peripheral arterial disease in elderly patients with Type-2 diabetes mellitus: A clinical study |
title_full_unstemmed | Risk factors for peripheral arterial disease in elderly patients with Type-2 diabetes mellitus: A clinical study |
title_short | Risk factors for peripheral arterial disease in elderly patients with Type-2 diabetes mellitus: A clinical study |
title_sort | risk factors for peripheral arterial disease in elderly patients with type-2 diabetes mellitus: a clinical study |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7501018/ https://www.ncbi.nlm.nih.gov/pubmed/32968406 http://dx.doi.org/10.12669/pjms.36.6.2906 |
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