Dengue and Zika virus infections are enhanced by live attenuated dengue vaccine but not by recombinant DSV4 vaccine candidate in mouse models

BACKGROUND: A tetravalent live attenuated dengue vaccine, Dengvaxia, sensitised naïve recipients to severe dengue illness upon a subsequent natural dengue infection and is suspected to be due to antibody-dependent enhancement (ADE). ADE has also been implicated in the severe neurological outcomes of...

Descripción completa

Detalles Bibliográficos
Autores principales: Shukla, Rahul, Beesetti, Hemalatha, Brown, Julia A., Ahuja, Richa, Ramasamy, Viswanathan, Shanmugam, Rajgokul K., Poddar, Ankur, Batra, Gaurav, Krammer, Florian, Lim, Jean K., Kale, Sachin, Lal, Altaf A., Swaminathan, Sathyamangalam, Khanna, Navin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7501058/
https://www.ncbi.nlm.nih.gov/pubmed/32949997
http://dx.doi.org/10.1016/j.ebiom.2020.102991

Ejemplares similares

Ejemplares similares