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Excess mortality due to COVID-19 in Germany

OBJECTIVES: The first wave of the SARS-CoV-2 pandemic in Germany lasted from week 10 to 23 in 2020. The aim is to provide estimates of excess mortality in Germany during this time. METHODS: We analyzed age-specific numbers of deaths per week from 2016 to week 26 in 2020. We used weekly mean numbers...

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Autores principales: Stang, Andreas, Standl, Fabian, Kowall, Bernd, Brune, Bastian, Böttcher, Juliane, Brinkmann, Marcus, Dittmer, Ulf, Jöckel, Karl-Heinz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The British Infection Association. Published by Elsevier Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7501062/
https://www.ncbi.nlm.nih.gov/pubmed/32956730
http://dx.doi.org/10.1016/j.jinf.2020.09.012
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author Stang, Andreas
Standl, Fabian
Kowall, Bernd
Brune, Bastian
Böttcher, Juliane
Brinkmann, Marcus
Dittmer, Ulf
Jöckel, Karl-Heinz
author_facet Stang, Andreas
Standl, Fabian
Kowall, Bernd
Brune, Bastian
Böttcher, Juliane
Brinkmann, Marcus
Dittmer, Ulf
Jöckel, Karl-Heinz
author_sort Stang, Andreas
collection PubMed
description OBJECTIVES: The first wave of the SARS-CoV-2 pandemic in Germany lasted from week 10 to 23 in 2020. The aim is to provide estimates of excess mortality in Germany during this time. METHODS: We analyzed age-specific numbers of deaths per week from 2016 to week 26 in 2020. We used weekly mean numbers of deaths of 2016–2019 to estimate expected weekly numbers for 2020. We estimated standardized mortality ratios (SMR) and 95% confidence intervals. RESULTS: During the first wave observed numbers of deaths were higher than expected for age groups 60–69, 80–89, and 90+. The age group 70–79 years did not show excess mortality. The net excess number of deaths for weeks 10–23 was +8,071. The overall SMR was 1•03 (95%CI 1•03–1•04). The largest increase occurred among people aged 80–89 and 90+ (SMR=1•08 and SMR=1•09). A sensitivity analysis that accounts for demographic changes revealed an overall SMR of 0•98 (95%CI 0•98–0•99) and a deficit of 4,926 deaths for week 10–23, 2020. CONCLUSIONS: The excess mortality existed for two months. The favorable course of the first wave may be explained by a younger age at infection at the beginning of the pandemic, lower contact rates, and a more efficient pandemic management.
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spelling pubmed-75010622020-09-21 Excess mortality due to COVID-19 in Germany Stang, Andreas Standl, Fabian Kowall, Bernd Brune, Bastian Böttcher, Juliane Brinkmann, Marcus Dittmer, Ulf Jöckel, Karl-Heinz J Infect Article OBJECTIVES: The first wave of the SARS-CoV-2 pandemic in Germany lasted from week 10 to 23 in 2020. The aim is to provide estimates of excess mortality in Germany during this time. METHODS: We analyzed age-specific numbers of deaths per week from 2016 to week 26 in 2020. We used weekly mean numbers of deaths of 2016–2019 to estimate expected weekly numbers for 2020. We estimated standardized mortality ratios (SMR) and 95% confidence intervals. RESULTS: During the first wave observed numbers of deaths were higher than expected for age groups 60–69, 80–89, and 90+. The age group 70–79 years did not show excess mortality. The net excess number of deaths for weeks 10–23 was +8,071. The overall SMR was 1•03 (95%CI 1•03–1•04). The largest increase occurred among people aged 80–89 and 90+ (SMR=1•08 and SMR=1•09). A sensitivity analysis that accounts for demographic changes revealed an overall SMR of 0•98 (95%CI 0•98–0•99) and a deficit of 4,926 deaths for week 10–23, 2020. CONCLUSIONS: The excess mortality existed for two months. The favorable course of the first wave may be explained by a younger age at infection at the beginning of the pandemic, lower contact rates, and a more efficient pandemic management. The British Infection Association. Published by Elsevier Ltd. 2020-11 2020-09-19 /pmc/articles/PMC7501062/ /pubmed/32956730 http://dx.doi.org/10.1016/j.jinf.2020.09.012 Text en © 2020 The British Infection Association. Published by Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Stang, Andreas
Standl, Fabian
Kowall, Bernd
Brune, Bastian
Böttcher, Juliane
Brinkmann, Marcus
Dittmer, Ulf
Jöckel, Karl-Heinz
Excess mortality due to COVID-19 in Germany
title Excess mortality due to COVID-19 in Germany
title_full Excess mortality due to COVID-19 in Germany
title_fullStr Excess mortality due to COVID-19 in Germany
title_full_unstemmed Excess mortality due to COVID-19 in Germany
title_short Excess mortality due to COVID-19 in Germany
title_sort excess mortality due to covid-19 in germany
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7501062/
https://www.ncbi.nlm.nih.gov/pubmed/32956730
http://dx.doi.org/10.1016/j.jinf.2020.09.012
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