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N- and O-glycosylation patterns and functional testing of CGB7 versus CGB3/5/8 variants of the human chorionic gonadotropin (hCG) beta subunit

The classical function of human chorionic gonadotropin (hCG) is its role in supporting pregnancy. hCG is a dimer consisting of two highly glycosylated subunits, alpha (CGA) and beta (CGB). The beta-hCG protein is encoded by CGB3, CGB5, CGB7 and CGB8 genes. CGB3, 5 and 8 code for an identical protein...

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Detalles Bibliográficos
Autores principales: Biskup, Karina, Blanchard, Véronique, Castillo-Binder, Paola, Alexander, Henry, Engeland, Kurt, Schug, Sindy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7501100/
https://www.ncbi.nlm.nih.gov/pubmed/32767150
http://dx.doi.org/10.1007/s10719-020-09936-w

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