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Identification of the Human DPR Promoter Element by using Machine Learning
The RNA polymerase II (Pol II) core promoter is the strategic site of convergence of the signals that lead to transcription initiation(1-5), but the downstream core promoter in humans has been difficult to decipher(1-3). Here, we analyze the human Pol II core promoter and use machine learning to gen...
Autores principales: | Vo ngoc, Long, Huang, Cassidy Yunjing, Cassidy, California Jack, Medrano, Claudia, Kadonaga, James T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7501168/ https://www.ncbi.nlm.nih.gov/pubmed/32908305 http://dx.doi.org/10.1038/s41586-020-2689-7 |
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