Association of APOE e2 genotype with Alzheimer’s and non-Alzheimer’s neurodegenerative pathologies

The apolipoprotein E (APOE) gene contains both the major common risk variant for late onset Alzheimer’s disease (AD), e4, and the major neuroprotective variant, e2. Here we examine the association of APOE e2 with multiple neurodegenerative pathologies, leveraging the NACC v. 10 database of 1557 brai...

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Detalles Bibliográficos
Autores principales: Goldberg, Terry E., Huey, Edward D., Devanand, D. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7501268/
https://www.ncbi.nlm.nih.gov/pubmed/32948752
http://dx.doi.org/10.1038/s41467-020-18198-x

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