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Dissecting clinical heterogeneity of bipolar disorder using multiple polygenic risk scores
Bipolar disorder (BD) has high clinical heterogeneity, frequent psychiatric comorbidities, and elevated suicide risk. To determine genetic differences between common clinical sub-phenotypes of BD, we performed a systematic polygenic risk score (PRS) analysis using multiple PRSs from a range of psych...
Autores principales: | Coombes, Brandon J., Markota, Matej, Mann, J. John, Colby, Colin, Stahl, Eli, Talati, Ardesheer, Pathak, Jyotishman, Weissman, Myrna M., McElroy, Susan L., Frye, Mark A., Biernacka, Joanna M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7501305/ https://www.ncbi.nlm.nih.gov/pubmed/32948743 http://dx.doi.org/10.1038/s41398-020-00996-y |
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