Cargando…

Bone ingrowth into open architecture PEEK interference screw after ACL reconstruction

PURPOSE: Open or fenestrated interference screw design that allow bone ingrowth is a concept for improved bone healing to softtissue graft and bone filling in bone tunnels after anterior cruciate ligament reconstruction (ACLR) The aim of the current study was to assess CT scanning evaluated bone ing...

Descripción completa

Detalles Bibliográficos
Autores principales: Lind, Martin, Nielsen, Torsten, Sørensen, Ole Gade, Mygind-Klavsen, Bjarne, Faunø, Peter, Leake-Gardner, Stacy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7501394/
https://www.ncbi.nlm.nih.gov/pubmed/32948982
http://dx.doi.org/10.1186/s40634-020-00285-z
_version_ 1783584017279352832
author Lind, Martin
Nielsen, Torsten
Sørensen, Ole Gade
Mygind-Klavsen, Bjarne
Faunø, Peter
Leake-Gardner, Stacy
author_facet Lind, Martin
Nielsen, Torsten
Sørensen, Ole Gade
Mygind-Klavsen, Bjarne
Faunø, Peter
Leake-Gardner, Stacy
author_sort Lind, Martin
collection PubMed
description PURPOSE: Open or fenestrated interference screw design that allow bone ingrowth is a concept for improved bone healing to softtissue graft and bone filling in bone tunnels after anterior cruciate ligament reconstruction (ACLR) The aim of the current study was to assess CT scanning evaluated bone ingrowth into an open architecture interference screws in the tibial tunnel of patients undergoing ACL with soft tissue grafts. It was hypothesized that open architecture interference screws would stimulate bone ingrowth into the screw cavities. METHODS: Twelve patients requiring ACLR were included. They underwent arthroscopic ACLR with semitendinosus−/gracilis tendon graft and an open architecture polyetheretherketone (PEEK) interference screw. The patients were scanned with a multi-slice CT scanner two weeks, six and twelve months postoperatively. On CT reconstruction slices bone ingrowth into the screw was measured. Subjective and objective clinical outcome international knee documentation committee score and instrumented knee laxity determination were collected. RESULTS: At six months no implants demonstrated more than 10% bone ingrowth. At twelve months 42% (5/12) implants had more than 10% bone ingrowth (p = 0.009). The average bone filling into the screws was 7.7%. There was no tunnel widening or cyst formation seen in relation to any of the implants. Subjective IKDC score improved significantly from 50.6 baseline to 80.1 at 24 month follow-up. Preoperative side-to-side knee laxity improved from 3.7 (2.1) to 1.4 (1.2) mm at twelve months. There were no serious adverse events in relation to the new open architecture thread PEEK interference screw during or after hamstring ACL reconstruction. CONCLUSION: The present study demonstrated that open architecture thread PEEK interference screw can stimulate bone ingrowth into the screws after soft tissue ACL reconstruction with at 12 months with an average bone filling into screws was 7.7%. Knee stability, functional, subjective and objective outcomes were similar to large volume ACL outcome studies. TRIAL REGISTRATION: The study was registered at ClinicalTrials # NCT02382341. 12-09-2014. LEVEL OF EVIDENCE: IV.
format Online
Article
Text
id pubmed-7501394
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Springer Berlin Heidelberg
record_format MEDLINE/PubMed
spelling pubmed-75013942020-10-01 Bone ingrowth into open architecture PEEK interference screw after ACL reconstruction Lind, Martin Nielsen, Torsten Sørensen, Ole Gade Mygind-Klavsen, Bjarne Faunø, Peter Leake-Gardner, Stacy J Exp Orthop Original Paper PURPOSE: Open or fenestrated interference screw design that allow bone ingrowth is a concept for improved bone healing to softtissue graft and bone filling in bone tunnels after anterior cruciate ligament reconstruction (ACLR) The aim of the current study was to assess CT scanning evaluated bone ingrowth into an open architecture interference screws in the tibial tunnel of patients undergoing ACL with soft tissue grafts. It was hypothesized that open architecture interference screws would stimulate bone ingrowth into the screw cavities. METHODS: Twelve patients requiring ACLR were included. They underwent arthroscopic ACLR with semitendinosus−/gracilis tendon graft and an open architecture polyetheretherketone (PEEK) interference screw. The patients were scanned with a multi-slice CT scanner two weeks, six and twelve months postoperatively. On CT reconstruction slices bone ingrowth into the screw was measured. Subjective and objective clinical outcome international knee documentation committee score and instrumented knee laxity determination were collected. RESULTS: At six months no implants demonstrated more than 10% bone ingrowth. At twelve months 42% (5/12) implants had more than 10% bone ingrowth (p = 0.009). The average bone filling into the screws was 7.7%. There was no tunnel widening or cyst formation seen in relation to any of the implants. Subjective IKDC score improved significantly from 50.6 baseline to 80.1 at 24 month follow-up. Preoperative side-to-side knee laxity improved from 3.7 (2.1) to 1.4 (1.2) mm at twelve months. There were no serious adverse events in relation to the new open architecture thread PEEK interference screw during or after hamstring ACL reconstruction. CONCLUSION: The present study demonstrated that open architecture thread PEEK interference screw can stimulate bone ingrowth into the screws after soft tissue ACL reconstruction with at 12 months with an average bone filling into screws was 7.7%. Knee stability, functional, subjective and objective outcomes were similar to large volume ACL outcome studies. TRIAL REGISTRATION: The study was registered at ClinicalTrials # NCT02382341. 12-09-2014. LEVEL OF EVIDENCE: IV. Springer Berlin Heidelberg 2020-09-18 /pmc/articles/PMC7501394/ /pubmed/32948982 http://dx.doi.org/10.1186/s40634-020-00285-z Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Original Paper
Lind, Martin
Nielsen, Torsten
Sørensen, Ole Gade
Mygind-Klavsen, Bjarne
Faunø, Peter
Leake-Gardner, Stacy
Bone ingrowth into open architecture PEEK interference screw after ACL reconstruction
title Bone ingrowth into open architecture PEEK interference screw after ACL reconstruction
title_full Bone ingrowth into open architecture PEEK interference screw after ACL reconstruction
title_fullStr Bone ingrowth into open architecture PEEK interference screw after ACL reconstruction
title_full_unstemmed Bone ingrowth into open architecture PEEK interference screw after ACL reconstruction
title_short Bone ingrowth into open architecture PEEK interference screw after ACL reconstruction
title_sort bone ingrowth into open architecture peek interference screw after acl reconstruction
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7501394/
https://www.ncbi.nlm.nih.gov/pubmed/32948982
http://dx.doi.org/10.1186/s40634-020-00285-z
work_keys_str_mv AT lindmartin boneingrowthintoopenarchitecturepeekinterferencescrewafteraclreconstruction
AT nielsentorsten boneingrowthintoopenarchitecturepeekinterferencescrewafteraclreconstruction
AT sørensenolegade boneingrowthintoopenarchitecturepeekinterferencescrewafteraclreconstruction
AT mygindklavsenbjarne boneingrowthintoopenarchitecturepeekinterferencescrewafteraclreconstruction
AT faunøpeter boneingrowthintoopenarchitecturepeekinterferencescrewafteraclreconstruction
AT leakegardnerstacy boneingrowthintoopenarchitecturepeekinterferencescrewafteraclreconstruction