Chimeric Antigen Receptor T Cell Therapy Targeting ICAM-1 in Gastric Cancer

Cancer therapy utilizing adoptive transfer of chimeric antigen receptor (CAR) T cells has demonstrated remarkable clinical outcomes in hematologic malignancies. However, CAR T cell application to solid tumors has had limited success, partly due to the lack of tumor-specific antigens and an immune-su...

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Detalles Bibliográficos
Autores principales: Jung, Minkyu, Yang, Yanping, McCloskey, Jaclyn E., Zaman, Marjan, Vedvyas, Yogindra, Zhang, Xianglan, Stefanova, Dessislava, Gray, Katherine D., Min, Irene M., Zarnegar, Raza, Choi, Yoon Young, Cheong, Jae-Ho, Noh, Sung Hoon, Rha, Sun Young, Chung, Hyun Cheol, Jin, Moonsoo M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7501410/
https://www.ncbi.nlm.nih.gov/pubmed/32995483
http://dx.doi.org/10.1016/j.omto.2020.08.009

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