Photo-controlled degradation of PLGA/Ti(3)C(2) hybrid coating on Mg-Sr alloy using near infrared light

A PLGA/Ti(3)C(2) hybrid coating was successfully deposited on the surface of magnesium-strontium (Mg-Sr) alloys. Compared with the corrosion current density (i(corr)) of the Mg-Sr alloy (7.13 × 10(−5) A/cm(2)), the modified samples (Mg/PLGA/Ti(3)C(2)) was lower by approximately four orders of magnit...

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Detalles Bibliográficos
Autores principales: Liu, Li, Huang, Bo, Liu, Xiangmei, Yuan, Wei, Zheng, Yufeng, Li, Zhaoyang, Yeung, Kelvin Wai Kwok, Zhu, Shengli, Liang, Yanqin, Cui, Zhenduo, Wu, Shuilin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7501411/
https://www.ncbi.nlm.nih.gov/pubmed/32995680
http://dx.doi.org/10.1016/j.bioactmat.2020.08.013
Descripción
Sumario:A PLGA/Ti(3)C(2) hybrid coating was successfully deposited on the surface of magnesium-strontium (Mg-Sr) alloys. Compared with the corrosion current density (i(corr)) of the Mg-Sr alloy (7.13 × 10(−5) A/cm(2)), the modified samples (Mg/PLGA/Ti(3)C(2)) was lower by approximately four orders of magnitude (7.65 × 10(−9) A/cm(2)). After near infrared 808 nm laser irradiation, the i(corr) of the modified samples increased to 3.48 × 10(−7) A/cm(2). The mechanism is that the local hyperthermia induced the free volume expansion of PLGA, and the increase in intermolecular gap enhanced the penetration of electrolytes. Meanwhile, the cytotoxicity study showed that the hybrid coating endowed the Mg-Sr alloy with enhanced biocompatibility.

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