Activation of Cannabinoid Receptor 2 Prevents Colitis-Associated Colon Cancer through Myeloid Cell De-activation Upstream of IL-22 Production

Intestinal disequilibrium leads to inflammatory bowel disease (IBD), and chronic inflammation predisposes to oncogenesis. Antigen-presenting dendritic cells (DCs) and macrophages can tip the equilibrium toward tolerance or pathology. Here we show that delta-9-tetrahydrocannabinol (THC) attenuates co...

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Detalles Bibliográficos
Autores principales: Becker, William, Alrafas, Haider Rasheed, Wilson, Kiesha, Miranda, Kathryn, Culpepper, Courtney, Chatzistamou, Ioulia, Cai, Guoshuai, Nagarkatti, Mitzi, Nagarkatti, Prakash S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7501437/
https://www.ncbi.nlm.nih.gov/pubmed/32942172
http://dx.doi.org/10.1016/j.isci.2020.101504

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