Case series: Failure of imaging & biochemical markers to capture disease progression in COVID-19

We report four individuals admitted for acute respiratory failure due to COVID-19 who demonstrated significant clinical improvement prior to discharge and subsequently were readmitted with worsening respiratory failure, elevated inflammatory markers and worsening chest imaging. We propose a multi-di...

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Autores principales: Dorey-Stein, Zachariah L., Myers, Catherine N., Kumaran, Maruti, Mamary, Albert J., Criner, Gerard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7501525/
https://www.ncbi.nlm.nih.gov/pubmed/32983862
http://dx.doi.org/10.1016/j.rmcr.2020.101227
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author Dorey-Stein, Zachariah L.
Myers, Catherine N.
Kumaran, Maruti
Mamary, Albert J.
Criner, Gerard J.
author_facet Dorey-Stein, Zachariah L.
Myers, Catherine N.
Kumaran, Maruti
Mamary, Albert J.
Criner, Gerard J.
author_sort Dorey-Stein, Zachariah L.
collection PubMed
description We report four individuals admitted for acute respiratory failure due to COVID-19 who demonstrated significant clinical improvement prior to discharge and subsequently were readmitted with worsening respiratory failure, elevated inflammatory markers and worsening chest imaging. We propose a multi-disciplinary discharge criterion to establish a safer discharge process including trending inflammatory markers, daily imaging and pursuing follow up CT chest, particularly in individuals with significant morbidities and health disparities.
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spelling pubmed-75015252020-09-21 Case series: Failure of imaging & biochemical markers to capture disease progression in COVID-19 Dorey-Stein, Zachariah L. Myers, Catherine N. Kumaran, Maruti Mamary, Albert J. Criner, Gerard J. Respir Med Case Rep Case Report We report four individuals admitted for acute respiratory failure due to COVID-19 who demonstrated significant clinical improvement prior to discharge and subsequently were readmitted with worsening respiratory failure, elevated inflammatory markers and worsening chest imaging. We propose a multi-disciplinary discharge criterion to establish a safer discharge process including trending inflammatory markers, daily imaging and pursuing follow up CT chest, particularly in individuals with significant morbidities and health disparities. Elsevier 2020-09-19 /pmc/articles/PMC7501525/ /pubmed/32983862 http://dx.doi.org/10.1016/j.rmcr.2020.101227 Text en © 2020 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Dorey-Stein, Zachariah L.
Myers, Catherine N.
Kumaran, Maruti
Mamary, Albert J.
Criner, Gerard J.
Case series: Failure of imaging & biochemical markers to capture disease progression in COVID-19
title Case series: Failure of imaging & biochemical markers to capture disease progression in COVID-19
title_full Case series: Failure of imaging & biochemical markers to capture disease progression in COVID-19
title_fullStr Case series: Failure of imaging & biochemical markers to capture disease progression in COVID-19
title_full_unstemmed Case series: Failure of imaging & biochemical markers to capture disease progression in COVID-19
title_short Case series: Failure of imaging & biochemical markers to capture disease progression in COVID-19
title_sort case series: failure of imaging & biochemical markers to capture disease progression in covid-19
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7501525/
https://www.ncbi.nlm.nih.gov/pubmed/32983862
http://dx.doi.org/10.1016/j.rmcr.2020.101227
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