Cargando…

An unexpected surprise: rare association of neuroendocrine tumours in inflammatory bowel disease

Neuroendocrine neoplasms are rare malignancies, more so when cancerous metastasis occurs without a known primary source. Here we discuss a case of an ulcerative colitis sufferer, 43-year-old lady presented with what was thought to be a flare up. Situation deteriorated and was taken to theatre to fin...

Descripción completa

Detalles Bibliográficos
Autores principales: Pat, Jackson J, Iqbal, Muhammad Rafaih, Wright, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7501529/
https://www.ncbi.nlm.nih.gov/pubmed/32973995
http://dx.doi.org/10.1093/jscr/rjaa306
_version_ 1783584045557350400
author Pat, Jackson J
Iqbal, Muhammad Rafaih
Wright, Christopher
author_facet Pat, Jackson J
Iqbal, Muhammad Rafaih
Wright, Christopher
author_sort Pat, Jackson J
collection PubMed
description Neuroendocrine neoplasms are rare malignancies, more so when cancerous metastasis occurs without a known primary source. Here we discuss a case of an ulcerative colitis sufferer, 43-year-old lady presented with what was thought to be a flare up. Situation deteriorated and was taken to theatre to find a significantly ischaemic colon, secondary to extensive venous thrombosis. The ischaemic bowel was resected alongside with what was thought to be a large, reactive lymph node. To our surprise, the resected lymph node returned with evidence of neuroendocrine neoplastic metastasis. Multiple laboratory and imaging investigations were performed in hope to identify the primary source. A second metastatic lymph node was identified and subsequently resected but the primary remains elusive. Currently, there are no visible evidences of active disease.
format Online
Article
Text
id pubmed-7501529
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Oxford University Press
record_format MEDLINE/PubMed
spelling pubmed-75015292020-09-23 An unexpected surprise: rare association of neuroendocrine tumours in inflammatory bowel disease Pat, Jackson J Iqbal, Muhammad Rafaih Wright, Christopher J Surg Case Rep Case Report Neuroendocrine neoplasms are rare malignancies, more so when cancerous metastasis occurs without a known primary source. Here we discuss a case of an ulcerative colitis sufferer, 43-year-old lady presented with what was thought to be a flare up. Situation deteriorated and was taken to theatre to find a significantly ischaemic colon, secondary to extensive venous thrombosis. The ischaemic bowel was resected alongside with what was thought to be a large, reactive lymph node. To our surprise, the resected lymph node returned with evidence of neuroendocrine neoplastic metastasis. Multiple laboratory and imaging investigations were performed in hope to identify the primary source. A second metastatic lymph node was identified and subsequently resected but the primary remains elusive. Currently, there are no visible evidences of active disease. Oxford University Press 2020-09-19 /pmc/articles/PMC7501529/ /pubmed/32973995 http://dx.doi.org/10.1093/jscr/rjaa306 Text en Published by Oxford University Press and JSCR Publishing Ltd. All rights reserved. © The Author(s) 2020. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Case Report
Pat, Jackson J
Iqbal, Muhammad Rafaih
Wright, Christopher
An unexpected surprise: rare association of neuroendocrine tumours in inflammatory bowel disease
title An unexpected surprise: rare association of neuroendocrine tumours in inflammatory bowel disease
title_full An unexpected surprise: rare association of neuroendocrine tumours in inflammatory bowel disease
title_fullStr An unexpected surprise: rare association of neuroendocrine tumours in inflammatory bowel disease
title_full_unstemmed An unexpected surprise: rare association of neuroendocrine tumours in inflammatory bowel disease
title_short An unexpected surprise: rare association of neuroendocrine tumours in inflammatory bowel disease
title_sort unexpected surprise: rare association of neuroendocrine tumours in inflammatory bowel disease
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7501529/
https://www.ncbi.nlm.nih.gov/pubmed/32973995
http://dx.doi.org/10.1093/jscr/rjaa306
work_keys_str_mv AT patjacksonj anunexpectedsurpriserareassociationofneuroendocrinetumoursininflammatoryboweldisease
AT iqbalmuhammadrafaih anunexpectedsurpriserareassociationofneuroendocrinetumoursininflammatoryboweldisease
AT wrightchristopher anunexpectedsurpriserareassociationofneuroendocrinetumoursininflammatoryboweldisease
AT patjacksonj unexpectedsurpriserareassociationofneuroendocrinetumoursininflammatoryboweldisease
AT iqbalmuhammadrafaih unexpectedsurpriserareassociationofneuroendocrinetumoursininflammatoryboweldisease
AT wrightchristopher unexpectedsurpriserareassociationofneuroendocrinetumoursininflammatoryboweldisease