FUT4siRNA augments the chemosensitivity of non-small cell lung cancer to cisplatin through activation of FOXO1-induced apoptosis

BACKGROUND: Increased fucosylation is associated with the chemoresistance phenotype. Meanwhile, fucosyltransferase IV (FUT4) amounts are frequently elevated in lung cancer and may be related to increased chemoresistance. METHODS: In the present work, FUT4’s role in cisplatin-induced apoptosis was as...

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Detalles Bibliográficos
Autores principales: Gao, Wei, Liang, Jinxiao, Ye, Yiru, Lu, Jinlan, Lin, Tongtong, Wang, Na, Dong, Jingyin, Pan, Jianping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7501616/
https://www.ncbi.nlm.nih.gov/pubmed/32948132
http://dx.doi.org/10.1186/s12885-020-07324-z

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