Development of a CD19 PET tracer for detecting B cells in a mouse model of multiple sclerosis

BACKGROUND: B cells play a central role in multiple sclerosis (MS) through production of injurious antibodies, secretion of pro-inflammatory cytokines, and antigen presentation. The therapeutic success of monoclonal antibodies (mAbs) targeting B cells in some but not all individuals suffering from M...

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Detalles Bibliográficos
Autores principales: Stevens, Marc Y., Cropper, Haley C., Lucot, Katherine L., Chaney, Aisling M., Lechtenberg, Kendra J., Jackson, Isaac M., Buckwalter, Marion S., James, Michelle L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7501720/
https://www.ncbi.nlm.nih.gov/pubmed/32948198
http://dx.doi.org/10.1186/s12974-020-01880-8

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