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Single-center experience of patients with interstitial lung diseases during the early days of the COVID-19 pandemic

INTRODUCTION: Patients with interstitial lung diseases (ILD) can be suspected to be at risk of experiencing a rapid flare-up due to COVID-19. However, no specific data are currently available for these patients. METHODS: We retrospectively analyzed a cohort of 401 patients with ILD and determined th...

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Autores principales: Guiot, J., Henket, M., Frix, A.N., Delvaux, M., Denis, A., Giltay, L., Thys, M., Gester, F., Moutschen, M., Corhay, J.L., Louis, R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Respiratory Society. Published by Elsevier B.V. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7501770/
https://www.ncbi.nlm.nih.gov/pubmed/32978099
http://dx.doi.org/10.1016/j.resinv.2020.08.006
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author Guiot, J.
Henket, M.
Frix, A.N.
Delvaux, M.
Denis, A.
Giltay, L.
Thys, M.
Gester, F.
Moutschen, M.
Corhay, J.L.
Louis, R.
author_facet Guiot, J.
Henket, M.
Frix, A.N.
Delvaux, M.
Denis, A.
Giltay, L.
Thys, M.
Gester, F.
Moutschen, M.
Corhay, J.L.
Louis, R.
author_sort Guiot, J.
collection PubMed
description INTRODUCTION: Patients with interstitial lung diseases (ILD) can be suspected to be at risk of experiencing a rapid flare-up due to COVID-19. However, no specific data are currently available for these patients. METHODS: We retrospectively analyzed a cohort of 401 patients with ILD and determined the proportion of patients hospitalized for proven severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and specific symptoms of COVID-19. RESULTS: We found that 1% of patients (n = 4) were hospitalized (1 in ICU) for COVID-19. In total, 310 of the 401 patients answered the phone call. Only 33 patients (0.08%) experienced specific symptoms of SARS-CoV-2 infection. CONCLUSION: Our study did not demonstrate any increased occurrence of severe COVID-19 in ILD patients compared to the global population. Based on our findings, we could not make any conclusion on the incidence rate of SARS-CoV-2 infection in patients with ILDs, or on the overall outcome of immunocompromised patients affected by COVID-19.
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spelling pubmed-75017702020-09-21 Single-center experience of patients with interstitial lung diseases during the early days of the COVID-19 pandemic Guiot, J. Henket, M. Frix, A.N. Delvaux, M. Denis, A. Giltay, L. Thys, M. Gester, F. Moutschen, M. Corhay, J.L. Louis, R. Respir Investig Rapid Communication INTRODUCTION: Patients with interstitial lung diseases (ILD) can be suspected to be at risk of experiencing a rapid flare-up due to COVID-19. However, no specific data are currently available for these patients. METHODS: We retrospectively analyzed a cohort of 401 patients with ILD and determined the proportion of patients hospitalized for proven severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and specific symptoms of COVID-19. RESULTS: We found that 1% of patients (n = 4) were hospitalized (1 in ICU) for COVID-19. In total, 310 of the 401 patients answered the phone call. Only 33 patients (0.08%) experienced specific symptoms of SARS-CoV-2 infection. CONCLUSION: Our study did not demonstrate any increased occurrence of severe COVID-19 in ILD patients compared to the global population. Based on our findings, we could not make any conclusion on the incidence rate of SARS-CoV-2 infection in patients with ILDs, or on the overall outcome of immunocompromised patients affected by COVID-19. The Japanese Respiratory Society. Published by Elsevier B.V. 2020-11 2020-09-19 /pmc/articles/PMC7501770/ /pubmed/32978099 http://dx.doi.org/10.1016/j.resinv.2020.08.006 Text en © 2020 The Japanese Respiratory Society. Published by Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Rapid Communication
Guiot, J.
Henket, M.
Frix, A.N.
Delvaux, M.
Denis, A.
Giltay, L.
Thys, M.
Gester, F.
Moutschen, M.
Corhay, J.L.
Louis, R.
Single-center experience of patients with interstitial lung diseases during the early days of the COVID-19 pandemic
title Single-center experience of patients with interstitial lung diseases during the early days of the COVID-19 pandemic
title_full Single-center experience of patients with interstitial lung diseases during the early days of the COVID-19 pandemic
title_fullStr Single-center experience of patients with interstitial lung diseases during the early days of the COVID-19 pandemic
title_full_unstemmed Single-center experience of patients with interstitial lung diseases during the early days of the COVID-19 pandemic
title_short Single-center experience of patients with interstitial lung diseases during the early days of the COVID-19 pandemic
title_sort single-center experience of patients with interstitial lung diseases during the early days of the covid-19 pandemic
topic Rapid Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7501770/
https://www.ncbi.nlm.nih.gov/pubmed/32978099
http://dx.doi.org/10.1016/j.resinv.2020.08.006
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