Vaccines for COVID-19: perspectives from nucleic acid vaccines to BCG as delivery vector system

This article discusses standard and new disruptive strategies in the race to develop an anti-COVID-19 vaccine. We also included new bioinformatic data from our group mapping immunodominant epitopes and structural analysis of the spike protein. Another innovative approach reviewed here is the use of...

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Detalles Bibliográficos
Autores principales: de Queiroz, Nina Marí G.P., Marinho, Fabio V., Chagas, Marcelo A., Leite, Luciana C.C., Homan, E. Jane, de Magalhães, Mariana T.Q., Oliveira, Sergio C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Institut Pasteur. Published by Elsevier Masson SAS. 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7501874/
https://www.ncbi.nlm.nih.gov/pubmed/32961274
http://dx.doi.org/10.1016/j.micinf.2020.09.004
Descripción
Sumario:This article discusses standard and new disruptive strategies in the race to develop an anti-COVID-19 vaccine. We also included new bioinformatic data from our group mapping immunodominant epitopes and structural analysis of the spike protein. Another innovative approach reviewed here is the use of BCG vaccine as priming strategy and/or delivery system expressing SARS-CoV-2 antigens.

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