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Non-contrast coronary magnetic resonance angiography: current frontiers and future horizons

Coronary magnetic resonance angiography (coronary MRA) is advantageous in its ability to assess coronary artery morphology and function without ionizing radiation or contrast media. However, technical limitations including reduced spatial resolution, long acquisition times, and low signal-to-noise r...

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Autores principales: Kato, Yoko, Ambale-Venkatesh, Bharath, Kassai, Yoshimori, Kasuboski, Larry, Schuijf, Joanne, Kapoor, Karan, Caruthers, Shelton, Lima, Joao A. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7502041/
https://www.ncbi.nlm.nih.gov/pubmed/32242282
http://dx.doi.org/10.1007/s10334-020-00834-8
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author Kato, Yoko
Ambale-Venkatesh, Bharath
Kassai, Yoshimori
Kasuboski, Larry
Schuijf, Joanne
Kapoor, Karan
Caruthers, Shelton
Lima, Joao A. C.
author_facet Kato, Yoko
Ambale-Venkatesh, Bharath
Kassai, Yoshimori
Kasuboski, Larry
Schuijf, Joanne
Kapoor, Karan
Caruthers, Shelton
Lima, Joao A. C.
author_sort Kato, Yoko
collection PubMed
description Coronary magnetic resonance angiography (coronary MRA) is advantageous in its ability to assess coronary artery morphology and function without ionizing radiation or contrast media. However, technical limitations including reduced spatial resolution, long acquisition times, and low signal-to-noise ratios prevent it from clinical routine utilization. Nonetheless, each of these limitations can be specifically addressed by a combination of novel technologies including super-resolution imaging, compressed sensing, and deep-learning reconstruction. In this paper, we first review the current clinical use and motivations for non-contrast coronary MRA, discuss currently available coronary MRA techniques, and highlight current technical developments that hold unique potential to optimize coronary MRA image acquisition and post-processing. In the final section, we examine the various research-based coronary MRA methods and metrics that can be leveraged to assess coronary stenosis severity, physiological function, and atherosclerotic plaque characterization. We specifically discuss how such technologies may contribute to the clinical translation of coronary MRA into a robust modality for routine clinical use.
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spelling pubmed-75020412020-10-01 Non-contrast coronary magnetic resonance angiography: current frontiers and future horizons Kato, Yoko Ambale-Venkatesh, Bharath Kassai, Yoshimori Kasuboski, Larry Schuijf, Joanne Kapoor, Karan Caruthers, Shelton Lima, Joao A. C. MAGMA Review Coronary magnetic resonance angiography (coronary MRA) is advantageous in its ability to assess coronary artery morphology and function without ionizing radiation or contrast media. However, technical limitations including reduced spatial resolution, long acquisition times, and low signal-to-noise ratios prevent it from clinical routine utilization. Nonetheless, each of these limitations can be specifically addressed by a combination of novel technologies including super-resolution imaging, compressed sensing, and deep-learning reconstruction. In this paper, we first review the current clinical use and motivations for non-contrast coronary MRA, discuss currently available coronary MRA techniques, and highlight current technical developments that hold unique potential to optimize coronary MRA image acquisition and post-processing. In the final section, we examine the various research-based coronary MRA methods and metrics that can be leveraged to assess coronary stenosis severity, physiological function, and atherosclerotic plaque characterization. We specifically discuss how such technologies may contribute to the clinical translation of coronary MRA into a robust modality for routine clinical use. Springer International Publishing 2020-04-02 2020 /pmc/articles/PMC7502041/ /pubmed/32242282 http://dx.doi.org/10.1007/s10334-020-00834-8 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Review
Kato, Yoko
Ambale-Venkatesh, Bharath
Kassai, Yoshimori
Kasuboski, Larry
Schuijf, Joanne
Kapoor, Karan
Caruthers, Shelton
Lima, Joao A. C.
Non-contrast coronary magnetic resonance angiography: current frontiers and future horizons
title Non-contrast coronary magnetic resonance angiography: current frontiers and future horizons
title_full Non-contrast coronary magnetic resonance angiography: current frontiers and future horizons
title_fullStr Non-contrast coronary magnetic resonance angiography: current frontiers and future horizons
title_full_unstemmed Non-contrast coronary magnetic resonance angiography: current frontiers and future horizons
title_short Non-contrast coronary magnetic resonance angiography: current frontiers and future horizons
title_sort non-contrast coronary magnetic resonance angiography: current frontiers and future horizons
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7502041/
https://www.ncbi.nlm.nih.gov/pubmed/32242282
http://dx.doi.org/10.1007/s10334-020-00834-8
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