Cargando…

Effect of sidt2 Gene on Cell Insulin Resistance and Its Molecular Mechanism

BACKGROUND: Sidt2 (SID1 transmembrane family, member 2) is a multiple transmembrane lysosomal membrane protein newly discovered in our previous study. In the previous study, we used gene targeting technique to make a mouse model of sidt2 gene knockout (sidt2(−/−)). It was found that sidt2(−/−) mice...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xiong, Qian-Ying, Xiong, Chao-Qun, Wang, Li-Zhuo, Gao, Jia-Lin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7502120/ https://www.ncbi.nlm.nih.gov/pubmed/32964053 http://dx.doi.org/10.1155/2020/4217607

Ejemplares similares

The Effects of Sidt2 on the Inflammatory Pathway in Mouse Mesangial Cells
por: Sun, Hui, et al.
Publicado: (2020)

Integrated Bioinformatics Data Analysis Reveals Prognostic Significance Of SIDT1 In Triple-Negative Breast Cancer
por: Wang, Ya, et al.
Publicado: (2019)

Perturbing the Normal Level of SIDT1 Suppresses the Naked ASO Effect
por: Takahashi, Masayuki, et al.
Publicado: (2021)

Impaired Glucose Tolerance in a Mouse Model of Sidt2 Deficiency
por: Gao, Jialin, et al.
Publicado: (2013)

Sidt2 is a key protein in the autophagy-lysosomal degradation pathway and is essential for the maintenance of kidney structure and filtration function
por: Geng, Meng-ya, et al.
Publicado: (2021)

SIDT2 RNA Transporter Promotes Lung and Gastrointestinal Tumor Development
por: Nguyen, Tan A., et al.
Publicado: (2019)

Lysosomal membrane protein SIDT2 mediates the direct uptake of DNA by lysosomes
por: Aizawa, Shu, et al.
Publicado: (2016)

Changes of lysosomal membrane permeabilization and lipid metabolism in sidt2 deficient mice
por: Meng, Yu, et al.
Publicado: (2018)

SIDT1-dependent absorption in the stomach mediates host uptake of dietary and orally administered microRNAs
por: Chen, Qun, et al.
Publicado: (2020)

Lysosomal putative RNA transporter SIDT2 mediates direct uptake of RNA by lysosomes
por: Aizawa, Shu, et al.
Publicado: (2016)

SIDT2 mediates gymnosis, the uptake of naked single-stranded oligonucleotides into living cells
por: Takahashi, Masayuki, et al.
Publicado: (2017)

Correlation of SIDT1 with Poor Prognosis and Immune Infiltration in Patients with Non-Small Cell Lung Cancer
por: Tian, Yubin, et al.
Publicado: (2022)

Gene-based association study for lipid traits in diverse cohorts implicates BACE1 and SIDT2 regulation in triglyceride levels
por: Andaleon, Angela, et al.
Publicado: (2018)

Interaction between SIDT2 and ABCA1 Variants with Nutrients on HDL-c Levels in Mexican Adults
por: León-Reyes, Guadalupe, et al.
Publicado: (2023)

Ultra-dense SNP genetic map construction and identification of SiDt gene controlling the determinate growth habit in Sesamum indicum L.
por: Zhang, Haiyang, et al.
Publicado: (2016)

The Variant rs1784042 of the SIDT2 Gene is Associated with Metabolic Syndrome through Low HDL-c Levels in a Mexican Population
por: León-Reyes, Guadalupe, et al.
Publicado: (2020)

SIDT2 Associates with Apolipoprotein A1 (ApoA1) and Facilitates ApoA1 Secretion in Hepatocytes
por: Sampieri, Alicia, et al.
Publicado: (2023)

Anticancer Activity of Diosgenin and Its Molecular Mechanism
por: Ren, Qun-li, et al.
Publicado: (2023)

Multiple genotype–phenotype association study reveals intronic variant pair on SIDT2 associated with metabolic syndrome in a Korean population
por: Moon, Sanghoon, et al.
Publicado: (2018)

Decreased HD-MIR2911 absorption in human subjects with the SIDT1 polymorphism fails to inhibit SARS-CoV-2 replication
por: Zhou, Zhen, et al.
Publicado: (2020)

Molecular Mechanisms of Hypothalamic Insulin Resistance
por: Ono, Hiraku
Publicado: (2019)

Topiramate-Induced Modulation of Hepatic Molecular Mechanisms: An Aspect for Its Anti-Insulin Resistant Effect
por: El-Abhar, Hanan S., et al.
Publicado: (2012)

Molecular Mechanisms of Glucocorticoid-Induced Insulin Resistance
por: Beaupere, Carine, et al.
Publicado: (2021)

Molecular mechanisms linking stress and insulin resistance
por: Yaribeygi, Habib, et al.
Publicado: (2022)

Current Studies on Molecular Mechanisms of Insulin Resistance
por: Pei, Jinli, et al.
Publicado: (2022)

SIDT1 plays a key role in type I IFN responses to nucleic acids in plasmacytoid dendritic cells and mediates the pathogenesis of an imiquimod-induced psoriasis model
por: Morell, María, et al.
Publicado: (2022)

Molecular mechanisms involved in hepatic steatosis and insulin resistance
por: Matsuzaka, Takashi, et al.
Publicado: (2011)

Molecular Mechanisms of Insulin Resistance in Chronic Kidney Disease
por: Thomas, Sandhya S., et al.
Publicado: (2015)

Molecular Mechanism of Insulin Resistance in Obesity and Type 2 Diabetes
por: Choi, Kangduk, et al.
Publicado: (2010)

Metabolic and Molecular Mechanisms of Macrophage Polarisation and Adipose Tissue Insulin Resistance
por: Orliaguet, Lucie, et al.
Publicado: (2020)

The Molecular Mechanisms of the Relationship between Insulin Resistance and Parkinson’s Disease Pathogenesis
por: Ruiz-Pozo, Viviana A., et al.
Publicado: (2023)

Research Progress on the Role of ABC Transporters in the Drug Resistance Mechanism of Intractable Epilepsy
por: Xiong, Jie, et al.
Publicado: (2015)

Molecular mechanisms underlying bacterial resistance to ceftazidime/avibactam
por: Xiong, Luying, et al.
Publicado: (2022)

Silencing of Two Insulin Receptor Genes Disrupts Nymph-Adult Transition of Alate Brown Citrus Aphid
por: Ding, Bi-Yue, et al.
Publicado: (2017)

Molecular Mechanisms Involved in Inflammation and Insulin Resistance in Chronic Diseases and Possible Interventions
por: Gorjão, Renata, et al.
Publicado: (2012)

The Molecular Mechanisms by Which Vitamin D Prevents Insulin Resistance and Associated Disorders
por: Szymczak-Pajor, Izabela, et al.
Publicado: (2020)

Role of Long Non-Coding RNAs and the Molecular Mechanisms Involved in Insulin Resistance
por: Tello-Flores, Vianet Argelia, et al.
Publicado: (2021)

Molecular Mechanisms for the Vicious Cycle between Insulin Resistance and the Inflammatory Response in Obesity
por: Szukiewicz, Dariusz
Publicado: (2023)

Prevention Effects and Possible Molecular Mechanism of Mulberry Leaf Extract and its Formulation on Rats with Insulin-Insensitivity
por: Liu, Yan, et al.
Publicado: (2016)

Effects of Vaspin on Insulin Resistance in Rats and Underlying Mechanisms
por: Liu, Shiwei, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_jrl8u2vkpau22m36v4q8g1gbie