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KRAS and PIK3CA bi-mutations predict a poor prognosis in colorectal cancer patients: A single-site report

STUDY RATIONALE: The coexistence of KRAS and PIK3CA mutations in cells implies potential synergistic hyperactivation of the Ras/MAPK and PI3K/Akt oncogenic pathways. Therefore, it is desirable to investigate the concomitant mutations of KRAS and PIK3CA in colorectal cancer (CRC) samples and whether...

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Detalles Bibliográficos
Autores principales:	Luo, Qianxin, Chen, Dianke, Fan, Xinjuan, Fu, Xinhui, Ma, Tenghui, Chen, Daici
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Neoplasia Press 2020
Materias:	Original article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7502368/ https://www.ncbi.nlm.nih.gov/pubmed/32947236 http://dx.doi.org/10.1016/j.tranon.2020.100874

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