Nrf2-regulated redox signaling in brain endothelial cells adapted to physiological oxygen levels: Consequences for sulforaphane mediated protection against hypoxia-reoxygenation

Ischemic stroke is associated with a surge in reactive oxygen species generation during reperfusion. The narrow therapeutic window for the delivery of intravenous thrombolysis and endovascular thrombectomy limits therapeutic options for patients. Thus, understanding the mechanisms regulating neurova...

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Detalles Bibliográficos
Autores principales: Warpsinski, Gabriela, Smith, Matthew J., Srivastava, Salil, Keeley, Thomas P., Siow, Richard C.M., Fraser, Paul A., Mann, Giovanni E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7502377/
https://www.ncbi.nlm.nih.gov/pubmed/32949969
http://dx.doi.org/10.1016/j.redox.2020.101708

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7502377/
https://www.ncbi.nlm.nih.gov/pubmed/32949969
http://dx.doi.org/10.1016/j.redox.2020.101708

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