ACEIs and ARBs and Their Correlation with COVID-19: A Review

Although some animal studies suggested that the use of ACEIs/ARBs could contribute for the prevention and treatment of the effects of the COVID-19 infection, there are also contradictory scenarios indicating that their use may exacerbate the deleterious conditions of the infection. As a result of th...

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Autores principales: Yehualashet, Awgichew Shewasinad, Belachew, Teshome Fentik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7502385/
https://www.ncbi.nlm.nih.gov/pubmed/32982336
http://dx.doi.org/10.2147/IDR.S264882
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author Yehualashet, Awgichew Shewasinad
Belachew, Teshome Fentik
author_facet Yehualashet, Awgichew Shewasinad
Belachew, Teshome Fentik
author_sort Yehualashet, Awgichew Shewasinad
collection PubMed
description Although some animal studies suggested that the use of ACEIs/ARBs could contribute for the prevention and treatment of the effects of the COVID-19 infection, there are also contradictory scenarios indicating that their use may exacerbate the deleterious conditions of the infection. As a result of the paradoxical issue of using ACEIs/ARBs during COVID-19, it is still an area requiring extended investigation to prove. Additionally, a trial evidence of their efficacy and the possible benefit risk analysis of these conventional drugs during COVID-19 in connection with other comorbidities like hypertension, heart failure, and renal disease associated with diabetes should also be addressed.
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spelling pubmed-75023852020-09-24 ACEIs and ARBs and Their Correlation with COVID-19: A Review Yehualashet, Awgichew Shewasinad Belachew, Teshome Fentik Infect Drug Resist Review Although some animal studies suggested that the use of ACEIs/ARBs could contribute for the prevention and treatment of the effects of the COVID-19 infection, there are also contradictory scenarios indicating that their use may exacerbate the deleterious conditions of the infection. As a result of the paradoxical issue of using ACEIs/ARBs during COVID-19, it is still an area requiring extended investigation to prove. Additionally, a trial evidence of their efficacy and the possible benefit risk analysis of these conventional drugs during COVID-19 in connection with other comorbidities like hypertension, heart failure, and renal disease associated with diabetes should also be addressed. Dove 2020-09-16 /pmc/articles/PMC7502385/ /pubmed/32982336 http://dx.doi.org/10.2147/IDR.S264882 Text en © 2020 Yehualashet and Belachew. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Review
Yehualashet, Awgichew Shewasinad
Belachew, Teshome Fentik
ACEIs and ARBs and Their Correlation with COVID-19: A Review
title ACEIs and ARBs and Their Correlation with COVID-19: A Review
title_full ACEIs and ARBs and Their Correlation with COVID-19: A Review
title_fullStr ACEIs and ARBs and Their Correlation with COVID-19: A Review
title_full_unstemmed ACEIs and ARBs and Their Correlation with COVID-19: A Review
title_short ACEIs and ARBs and Their Correlation with COVID-19: A Review
title_sort aceis and arbs and their correlation with covid-19: a review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7502385/
https://www.ncbi.nlm.nih.gov/pubmed/32982336
http://dx.doi.org/10.2147/IDR.S264882
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