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Mesencephalic Astrocyte-Derived Neurotrophic Factor, a Prognostic Factor of Cholangiocarcinoma, Affects Sorafenib Sensitivity of Cholangiocarcinoma Cells by Deteriorating ER Stress

PURPOSE: Intrahepatic cholangiocarcinoma (ICC) is an aggressive malignant tumor characterized by high malignancy and poor prognosis. Although the efficacy of sorafenib against cholangiocarcinoma cell lines has been demonstrated in vivo and in vitro, limited clinical data are available on the efficacy...

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Detalles Bibliográficos
Autores principales: He, Jingyi, Li, Guangbing, Liu, Xihan, Ma, Liye, Zhang, Jiayao, Zheng, Shunzhen, Wang, Jianping, Liu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7502388/
https://www.ncbi.nlm.nih.gov/pubmed/32982305
http://dx.doi.org/10.2147/OTT.S245575

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