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Biotechnology of Rhodococcus for the production of valuable compounds
ABSTRACT: Bacteria belonging to Rhodococcus genus represent ideal candidates for microbial biotechnology applications because of their metabolic versatility, ability to degrade a wide range of organic compounds, and resistance to various stress conditions, such as metal toxicity, desiccation, and hi...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Springer Berlin Heidelberg
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7502451/ https://www.ncbi.nlm.nih.gov/pubmed/32918579 http://dx.doi.org/10.1007/s00253-020-10861-z |
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author | Cappelletti, Martina Presentato, Alessandro Piacenza, Elena Firrincieli, Andrea Turner, Raymond J. Zannoni, Davide |
author_facet | Cappelletti, Martina Presentato, Alessandro Piacenza, Elena Firrincieli, Andrea Turner, Raymond J. Zannoni, Davide |
author_sort | Cappelletti, Martina |
collection | PubMed |
description | ABSTRACT: Bacteria belonging to Rhodococcus genus represent ideal candidates for microbial biotechnology applications because of their metabolic versatility, ability to degrade a wide range of organic compounds, and resistance to various stress conditions, such as metal toxicity, desiccation, and high concentration of organic solvents. Rhodococcus spp. strains have also peculiar biosynthetic activities that contribute to their strong persistence in harsh and contaminated environments and provide them a competitive advantage over other microorganisms. This review is focused on the metabolic features of Rhodococcus genus and their potential use in biotechnology strategies for the production of compounds with environmental, industrial, and medical relevance such as biosurfactants, bioflocculants, carotenoids, triacylglycerols, polyhydroxyalkanoate, siderophores, antimicrobials, and metal-based nanostructures. These biosynthetic capacities can also be exploited to obtain high value-added products from low-cost substrates (industrial wastes and contaminants), offering the possibility to efficiently recover valuable resources and providing possible waste disposal solutions. Rhodococcus spp. strains have also recently been pointed out as a source of novel bioactive molecules highlighting the need to extend the knowledge on biosynthetic capacities of members of this genus and their potential utilization in the framework of bioeconomy. KEY POINTS: • Rhodococcus possesses promising biosynthetic and bioconversion capacities. • Rhodococcus bioconversion capacities can provide waste disposal solutions. • Rhodococcus bioproducts have environmental, industrial, and medical relevance. [Figure: see text] |
format | Online Article Text |
id | pubmed-7502451 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-75024512020-10-01 Biotechnology of Rhodococcus for the production of valuable compounds Cappelletti, Martina Presentato, Alessandro Piacenza, Elena Firrincieli, Andrea Turner, Raymond J. Zannoni, Davide Appl Microbiol Biotechnol Mini-Review ABSTRACT: Bacteria belonging to Rhodococcus genus represent ideal candidates for microbial biotechnology applications because of their metabolic versatility, ability to degrade a wide range of organic compounds, and resistance to various stress conditions, such as metal toxicity, desiccation, and high concentration of organic solvents. Rhodococcus spp. strains have also peculiar biosynthetic activities that contribute to their strong persistence in harsh and contaminated environments and provide them a competitive advantage over other microorganisms. This review is focused on the metabolic features of Rhodococcus genus and their potential use in biotechnology strategies for the production of compounds with environmental, industrial, and medical relevance such as biosurfactants, bioflocculants, carotenoids, triacylglycerols, polyhydroxyalkanoate, siderophores, antimicrobials, and metal-based nanostructures. These biosynthetic capacities can also be exploited to obtain high value-added products from low-cost substrates (industrial wastes and contaminants), offering the possibility to efficiently recover valuable resources and providing possible waste disposal solutions. Rhodococcus spp. strains have also recently been pointed out as a source of novel bioactive molecules highlighting the need to extend the knowledge on biosynthetic capacities of members of this genus and their potential utilization in the framework of bioeconomy. KEY POINTS: • Rhodococcus possesses promising biosynthetic and bioconversion capacities. • Rhodococcus bioconversion capacities can provide waste disposal solutions. • Rhodococcus bioproducts have environmental, industrial, and medical relevance. [Figure: see text] Springer Berlin Heidelberg 2020-09-12 2020 /pmc/articles/PMC7502451/ /pubmed/32918579 http://dx.doi.org/10.1007/s00253-020-10861-z Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Mini-Review Cappelletti, Martina Presentato, Alessandro Piacenza, Elena Firrincieli, Andrea Turner, Raymond J. Zannoni, Davide Biotechnology of Rhodococcus for the production of valuable compounds |
title | Biotechnology of Rhodococcus for the production of valuable compounds |
title_full | Biotechnology of Rhodococcus for the production of valuable compounds |
title_fullStr | Biotechnology of Rhodococcus for the production of valuable compounds |
title_full_unstemmed | Biotechnology of Rhodococcus for the production of valuable compounds |
title_short | Biotechnology of Rhodococcus for the production of valuable compounds |
title_sort | biotechnology of rhodococcus for the production of valuable compounds |
topic | Mini-Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7502451/ https://www.ncbi.nlm.nih.gov/pubmed/32918579 http://dx.doi.org/10.1007/s00253-020-10861-z |
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