Cell–cell adhesion and 3D matrix confinement determine jamming transitions in breast cancer invasion

Plasticity of cancer invasion and metastasis depends on the ability of cancer cells to switch between collective and single-cell dissemination, controlled by cadherin-mediated cell–cell junctions. In clinical samples, E-cadherin-expressing and -deficient tumours both invade collectively and metastas...

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Detalles Bibliográficos
Autores principales: Ilina, Olga, Gritsenko, Pavlo G., Syga, Simon, Lippoldt, Jürgen, La Porta, Caterina A. M., Chepizhko, Oleksandr, Grosser, Steffen, Vullings, Manon, Bakker, Gert-Jan, Starruß, Jörn, Bult, Peter, Zapperi, Stefano, Käs, Josef A., Deutsch, Andreas, Friedl, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7502685/
https://www.ncbi.nlm.nih.gov/pubmed/32839548
http://dx.doi.org/10.1038/s41556-020-0552-6

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