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Frontal lobe epilepsy manifesting as vertigo: a case report and literature review
Frontal lobe epilepsy is a common neurological disorder with a broad spectrum of symptoms. Frontal lobe epilepsy presenting with vertigo is extremely rare, and the relevant pathogenesis remains unclear. Herein, we report a case of frontal lobe epilepsy manifesting as vertigo, and we review the relev...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7502690/ https://www.ncbi.nlm.nih.gov/pubmed/32877235 http://dx.doi.org/10.1177/0300060520946166 |
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author | Jiang, Yongning Zhou, Xiangqin |
author_facet | Jiang, Yongning Zhou, Xiangqin |
author_sort | Jiang, Yongning |
collection | PubMed |
description | Frontal lobe epilepsy is a common neurological disorder with a broad spectrum of symptoms. Frontal lobe epilepsy presenting with vertigo is extremely rare, and the relevant pathogenesis remains unclear. Herein, we report a case of frontal lobe epilepsy manifesting as vertigo, and we review the relevant literature. A 34-year-old woman presented with a 10-year history of general tonic–clonic seizures. In the month prior to admission, she experienced nocturnal seizures on two occasions. Video electroencephalogram monitoring showed frequent clinical seizures during which the patient felt transient vertigo. The ictal electroencephalogram revealed a medium-amplitude spike and slow wave complex originating from the frontal lobes. The patient was treated with oral sodium valproate, levetiracetam, and lamotrigine. After a 6-month follow-up period, her seizures were well controlled. Our findings expand the symptom spectrum of epilepsy, suggesting that vertigo can be an uncommon clinical manifestation of frontal lobe epilepsy. Although the pathological correlation between vertigo and epilepsy remains elusive, our findings indicate that vestibular cortical neurons may participate in periodic epileptiform discharges of the frontal lobe. Clinicians should be aware of a potential diagnosis of epilepsy in patients presenting with vertigo as the onset symptom because this condition is usually underdiagnosed. |
format | Online Article Text |
id | pubmed-7502690 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-75026902020-09-28 Frontal lobe epilepsy manifesting as vertigo: a case report and literature review Jiang, Yongning Zhou, Xiangqin J Int Med Res Case Report Frontal lobe epilepsy is a common neurological disorder with a broad spectrum of symptoms. Frontal lobe epilepsy presenting with vertigo is extremely rare, and the relevant pathogenesis remains unclear. Herein, we report a case of frontal lobe epilepsy manifesting as vertigo, and we review the relevant literature. A 34-year-old woman presented with a 10-year history of general tonic–clonic seizures. In the month prior to admission, she experienced nocturnal seizures on two occasions. Video electroencephalogram monitoring showed frequent clinical seizures during which the patient felt transient vertigo. The ictal electroencephalogram revealed a medium-amplitude spike and slow wave complex originating from the frontal lobes. The patient was treated with oral sodium valproate, levetiracetam, and lamotrigine. After a 6-month follow-up period, her seizures were well controlled. Our findings expand the symptom spectrum of epilepsy, suggesting that vertigo can be an uncommon clinical manifestation of frontal lobe epilepsy. Although the pathological correlation between vertigo and epilepsy remains elusive, our findings indicate that vestibular cortical neurons may participate in periodic epileptiform discharges of the frontal lobe. Clinicians should be aware of a potential diagnosis of epilepsy in patients presenting with vertigo as the onset symptom because this condition is usually underdiagnosed. SAGE Publications 2020-09-02 /pmc/articles/PMC7502690/ /pubmed/32877235 http://dx.doi.org/10.1177/0300060520946166 Text en © The Author(s) 2020 https://creativecommons.org/licenses/by-nc/4.0/ Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Case Report Jiang, Yongning Zhou, Xiangqin Frontal lobe epilepsy manifesting as vertigo: a case report and literature review |
title | Frontal lobe epilepsy manifesting as vertigo: a case report and
literature review |
title_full | Frontal lobe epilepsy manifesting as vertigo: a case report and
literature review |
title_fullStr | Frontal lobe epilepsy manifesting as vertigo: a case report and
literature review |
title_full_unstemmed | Frontal lobe epilepsy manifesting as vertigo: a case report and
literature review |
title_short | Frontal lobe epilepsy manifesting as vertigo: a case report and
literature review |
title_sort | frontal lobe epilepsy manifesting as vertigo: a case report and
literature review |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7502690/ https://www.ncbi.nlm.nih.gov/pubmed/32877235 http://dx.doi.org/10.1177/0300060520946166 |
work_keys_str_mv | AT jiangyongning frontallobeepilepsymanifestingasvertigoacasereportandliteraturereview AT zhouxiangqin frontallobeepilepsymanifestingasvertigoacasereportandliteraturereview |