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Analysis of β(2)AR-G(s) and β(2)AR-G(i) complex formation by NMR spectroscopy

The β(2)-adrenergic receptor (β(2)AR) is a prototypical G protein-coupled receptor (GPCR) that preferentially couples to the stimulatory G protein G(s) and stimulates cAMP formation. Functional studies have shown that the β(2)AR also couples to inhibitory G protein G(i), activation of which inhibits...

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Detalles Bibliográficos
Autores principales:	Ma, Xiuyan, Hu, Yunfei, Batebi, Hossein, Heng, Jie, Xu, Jun, Liu, Xiangyu, Niu, Xiaogang, Li, Hongwei, Hildebrand, Peter W., Jin, Changwen, Kobilka, Brian K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2020
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7502740/ https://www.ncbi.nlm.nih.gov/pubmed/32868434 http://dx.doi.org/10.1073/pnas.2009786117

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