STING Mediates Lupus via the Activation of Conventional Dendritic Cell Maturation and Plasmacytoid Dendritic Cell Differentiation

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Signaling through stimulator of interferon genes (STING) leads to the production of type I interferons (IFN-Is) and inflammatory cytokines. A gain-of-function mutation in STING was identified in an autoinflammatory disease (STING-associated vasculopathy with onset in infancy; SAVI). The expression o...

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Detalles Bibliográficos
Autores principales: Thim-uam, Arthid, Prabakaran, Thaneas, Tansakul, Mookmanee, Makjaroen, Jiradej, Wongkongkathep, Piriya, Chantaravisoot, Naphat, Saethang, Thammakorn, Leelahavanichkul, Asada, Benjachat, Thitima, Paludan, Søren, Pisitkun, Trairak, Pisitkun, Prapaporn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7502826/
https://www.ncbi.nlm.nih.gov/pubmed/33083760
http://dx.doi.org/10.1016/j.isci.2020.101530
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