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The Association Between Chronic Kidney Disease and New Onset Renal Replacement Therapy on the Outcome of COVID-19 Patients: A Meta-analysis

OBJECTIVE: The aim of the study was to evaluate the association between chronic kidney disease (CKD) and new onset renal replacement therapy (RRT) with the outcome of Coronavirus Disease 2019 (COVID-19) in patients. METHODOLOGY: A systematic literature search from several databases was performed on...

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Autores principales: Pranata, Raymond, Supriyadi, Rudi, Huang, Ian, Permana, Hikmat, Lim, Michael Anthonius, Yonas, Emir, Soetedjo, Nanny Natalia M, Lukito, Antonia Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7502996/
https://www.ncbi.nlm.nih.gov/pubmed/32994700
http://dx.doi.org/10.1177/1179548420959165
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author Pranata, Raymond
Supriyadi, Rudi
Huang, Ian
Permana, Hikmat
Lim, Michael Anthonius
Yonas, Emir
Soetedjo, Nanny Natalia M
Lukito, Antonia Anna
author_facet Pranata, Raymond
Supriyadi, Rudi
Huang, Ian
Permana, Hikmat
Lim, Michael Anthonius
Yonas, Emir
Soetedjo, Nanny Natalia M
Lukito, Antonia Anna
author_sort Pranata, Raymond
collection PubMed
description OBJECTIVE: The aim of the study was to evaluate the association between chronic kidney disease (CKD) and new onset renal replacement therapy (RRT) with the outcome of Coronavirus Disease 2019 (COVID-19) in patients. METHODOLOGY: A systematic literature search from several databases was performed on studies that assessed CKD, use of RRT, and the outcome of COVID-19. The composite of poor outcome consisted of mortality, severe COVID-19, acute respiratory distress syndrome (ARDS), need for intensive care, and use of mechanical ventilator. RESULTS: Nineteen studies with a total of 7216 patients were included. CKD was associated with increased composite poor outcome (RR 2.63 [1.33, 5.17], P = .03; I(2) = 51%, P = .01) and its subgroup, consisting of mortality (RR 3.47 [1.36, 8.86], P = .009; I(2) = 14%, P = .32) and severe COVID-19 (RR 2.89 [0.98, 8.46], P = .05; I(2) = 57%, P = .04). RRT was associated with increased composite poor outcome (RR 18.04 [4.44, 73.25], P < .001; I(2) = 87%, P < .001), including mortality (RR 26.02 [5.01, 135.13], P < .001; I(2) = 60%, P = .06), severe COVID-19 (RR 12.95 [1.93, 86.82], P = .008; I(2) = 81%, P < .001), intensive care (IC) (RR 14.22 [1.76, 114.62], P < .01; I(2) = 0%, P < .98), and use of mechanical ventilator (RR 34.39 [4.63, 255.51], P < .0005). CONCLUSION: CKD and new-onset RRT were associated with poor outcome in patients with COVID-19.
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spelling pubmed-75029962020-09-28 The Association Between Chronic Kidney Disease and New Onset Renal Replacement Therapy on the Outcome of COVID-19 Patients: A Meta-analysis Pranata, Raymond Supriyadi, Rudi Huang, Ian Permana, Hikmat Lim, Michael Anthonius Yonas, Emir Soetedjo, Nanny Natalia M Lukito, Antonia Anna Clin Med Insights Circ Respir Pulm Med Meta-Analysis OBJECTIVE: The aim of the study was to evaluate the association between chronic kidney disease (CKD) and new onset renal replacement therapy (RRT) with the outcome of Coronavirus Disease 2019 (COVID-19) in patients. METHODOLOGY: A systematic literature search from several databases was performed on studies that assessed CKD, use of RRT, and the outcome of COVID-19. The composite of poor outcome consisted of mortality, severe COVID-19, acute respiratory distress syndrome (ARDS), need for intensive care, and use of mechanical ventilator. RESULTS: Nineteen studies with a total of 7216 patients were included. CKD was associated with increased composite poor outcome (RR 2.63 [1.33, 5.17], P = .03; I(2) = 51%, P = .01) and its subgroup, consisting of mortality (RR 3.47 [1.36, 8.86], P = .009; I(2) = 14%, P = .32) and severe COVID-19 (RR 2.89 [0.98, 8.46], P = .05; I(2) = 57%, P = .04). RRT was associated with increased composite poor outcome (RR 18.04 [4.44, 73.25], P < .001; I(2) = 87%, P < .001), including mortality (RR 26.02 [5.01, 135.13], P < .001; I(2) = 60%, P = .06), severe COVID-19 (RR 12.95 [1.93, 86.82], P = .008; I(2) = 81%, P < .001), intensive care (IC) (RR 14.22 [1.76, 114.62], P < .01; I(2) = 0%, P < .98), and use of mechanical ventilator (RR 34.39 [4.63, 255.51], P < .0005). CONCLUSION: CKD and new-onset RRT were associated with poor outcome in patients with COVID-19. SAGE Publications 2020-09-17 /pmc/articles/PMC7502996/ /pubmed/32994700 http://dx.doi.org/10.1177/1179548420959165 Text en © The Author(s) 2020 https://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Meta-Analysis
Pranata, Raymond
Supriyadi, Rudi
Huang, Ian
Permana, Hikmat
Lim, Michael Anthonius
Yonas, Emir
Soetedjo, Nanny Natalia M
Lukito, Antonia Anna
The Association Between Chronic Kidney Disease and New Onset Renal Replacement Therapy on the Outcome of COVID-19 Patients: A Meta-analysis
title The Association Between Chronic Kidney Disease and New Onset Renal Replacement Therapy on the Outcome of COVID-19 Patients: A Meta-analysis
title_full The Association Between Chronic Kidney Disease and New Onset Renal Replacement Therapy on the Outcome of COVID-19 Patients: A Meta-analysis
title_fullStr The Association Between Chronic Kidney Disease and New Onset Renal Replacement Therapy on the Outcome of COVID-19 Patients: A Meta-analysis
title_full_unstemmed The Association Between Chronic Kidney Disease and New Onset Renal Replacement Therapy on the Outcome of COVID-19 Patients: A Meta-analysis
title_short The Association Between Chronic Kidney Disease and New Onset Renal Replacement Therapy on the Outcome of COVID-19 Patients: A Meta-analysis
title_sort association between chronic kidney disease and new onset renal replacement therapy on the outcome of covid-19 patients: a meta-analysis
topic Meta-Analysis
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7502996/
https://www.ncbi.nlm.nih.gov/pubmed/32994700
http://dx.doi.org/10.1177/1179548420959165
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