Patients With Lung Cancer Have High Susceptibility of COVID-19: A Retrospective Study in Wuhan, China

Patients with lung cancer are presumed to be at high risk from COVID-19 infection due to underlying malignancy. A total of 31 COVID-19 patients with pre-diagnosed lung cancer and 186 age and sex matched COVID-19 patients without cancer in 6 hospitals in Wuhan, China were identified in our study. The...

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Detalles Bibliográficos
Autores principales: Dai, Meng-Yuan, Chen, Zhen, Leng, Yan, Wu, Meng, Liu, Yu, Zhou, Fuxiang, Ming, Chen, Shao, Ningyi, Liu, Miao, Cai, Hongbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Original Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7503035/
https://www.ncbi.nlm.nih.gov/pubmed/32938231
http://dx.doi.org/10.1177/1073274820960467
Descripción
Sumario:Patients with lung cancer are presumed to be at high risk from COVID-19 infection due to underlying malignancy. A total of 31 COVID-19 patients with pre-diagnosed lung cancer and 186 age and sex matched COVID-19 patients without cancer in 6 hospitals in Wuhan, China were identified in our study. There was a significantly higher level of IL-6 in lung cancer group showed by multifactorial analysis. The restricted mean survival time in 10, 20, and 53 days in COVID-19 patients with lung cancer were ealier than non-cancer COVID-19 patients in the same observation time (all P values < 0.05). Our results indicated that pre-diagnosed lung cancer was associated with higher morbidity and mortality in COVID-19 patients.

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