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Bacillus subtilis ANSB01G culture alleviates oxidative stress and cell apoptosis induced by dietary zearalenone in first-parity gestation sows
This study was conducted to evaluate the alleviation of Bacillus subtilis ANSB01G culture as zearalenone (ZEA) biodegradation agent on oxidative stress, cell apoptosis and fecal ZEA residue in the first parity gestation sows during the gestation. A total of 80 first-parity gilts (Yorkshire × Landrac...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
KeAi Publishing
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7503068/ https://www.ncbi.nlm.nih.gov/pubmed/33005771 http://dx.doi.org/10.1016/j.aninu.2020.03.011 |
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author | Zhou, Jianchuan Ao, Xiang Lei, Yuanpei Ji, Cheng Ma, Qiugang |
author_facet | Zhou, Jianchuan Ao, Xiang Lei, Yuanpei Ji, Cheng Ma, Qiugang |
author_sort | Zhou, Jianchuan |
collection | PubMed |
description | This study was conducted to evaluate the alleviation of Bacillus subtilis ANSB01G culture as zearalenone (ZEA) biodegradation agent on oxidative stress, cell apoptosis and fecal ZEA residue in the first parity gestation sows during the gestation. A total of 80 first-parity gilts (Yorkshire × Landrace) were randomly allocated to 4 dietary treatments with 20 replications per treatment and one gilt per replicate. The dietary treatments were as follows: CO (positive control); MO (negative control, ZEA level at 246 μg/kg diet); COA (CO + B. subtilis ANSB01G culture with 2 × 10(9) CFU/kg diet); MOA (MO + ZEA level at 260 μg/kg diet + B. subtilis ANSB01G culture with 2 × 10(9) CFU/kg diet). The experiment lasted for the whole gestation period of sows. Results showed that feeding the diet naturally contaminated with low-dose ZEA caused an increase of cell apoptosis in organ and the residual ZEA in feces as well as a decrease of antioxidant function in serum. The addition of B. subtilis ANSB01G culture in the diets can effectively alleviate the status of oxidative stress and cell apoptosis induced by ZEA in diets of gestation sows, as well as decrease the content of residual ZEA in feces. |
format | Online Article Text |
id | pubmed-7503068 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | KeAi Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-75030682020-09-30 Bacillus subtilis ANSB01G culture alleviates oxidative stress and cell apoptosis induced by dietary zearalenone in first-parity gestation sows Zhou, Jianchuan Ao, Xiang Lei, Yuanpei Ji, Cheng Ma, Qiugang Anim Nutr Short Communication This study was conducted to evaluate the alleviation of Bacillus subtilis ANSB01G culture as zearalenone (ZEA) biodegradation agent on oxidative stress, cell apoptosis and fecal ZEA residue in the first parity gestation sows during the gestation. A total of 80 first-parity gilts (Yorkshire × Landrace) were randomly allocated to 4 dietary treatments with 20 replications per treatment and one gilt per replicate. The dietary treatments were as follows: CO (positive control); MO (negative control, ZEA level at 246 μg/kg diet); COA (CO + B. subtilis ANSB01G culture with 2 × 10(9) CFU/kg diet); MOA (MO + ZEA level at 260 μg/kg diet + B. subtilis ANSB01G culture with 2 × 10(9) CFU/kg diet). The experiment lasted for the whole gestation period of sows. Results showed that feeding the diet naturally contaminated with low-dose ZEA caused an increase of cell apoptosis in organ and the residual ZEA in feces as well as a decrease of antioxidant function in serum. The addition of B. subtilis ANSB01G culture in the diets can effectively alleviate the status of oxidative stress and cell apoptosis induced by ZEA in diets of gestation sows, as well as decrease the content of residual ZEA in feces. KeAi Publishing 2020-09 2020-07-06 /pmc/articles/PMC7503068/ /pubmed/33005771 http://dx.doi.org/10.1016/j.aninu.2020.03.011 Text en © 2020 Chinese Association of Animal Science and Veterinary Medicine. Production and hosting by Elsevier B.V. on behalf of KeAi Communications Co., Ltd. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Short Communication Zhou, Jianchuan Ao, Xiang Lei, Yuanpei Ji, Cheng Ma, Qiugang Bacillus subtilis ANSB01G culture alleviates oxidative stress and cell apoptosis induced by dietary zearalenone in first-parity gestation sows |
title | Bacillus subtilis ANSB01G culture alleviates oxidative stress and cell apoptosis induced by dietary zearalenone in first-parity gestation sows |
title_full | Bacillus subtilis ANSB01G culture alleviates oxidative stress and cell apoptosis induced by dietary zearalenone in first-parity gestation sows |
title_fullStr | Bacillus subtilis ANSB01G culture alleviates oxidative stress and cell apoptosis induced by dietary zearalenone in first-parity gestation sows |
title_full_unstemmed | Bacillus subtilis ANSB01G culture alleviates oxidative stress and cell apoptosis induced by dietary zearalenone in first-parity gestation sows |
title_short | Bacillus subtilis ANSB01G culture alleviates oxidative stress and cell apoptosis induced by dietary zearalenone in first-parity gestation sows |
title_sort | bacillus subtilis ansb01g culture alleviates oxidative stress and cell apoptosis induced by dietary zearalenone in first-parity gestation sows |
topic | Short Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7503068/ https://www.ncbi.nlm.nih.gov/pubmed/33005771 http://dx.doi.org/10.1016/j.aninu.2020.03.011 |
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