Concordance of CSF measures of Alzheimer's pathology with amyloid PET status in a preclinical cohort: A comparison of Lumipulse and established immunoassays

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INTRODUCTION: We assessed the concordance of cerebrospinal fluid (CSF) amyloid beta (Aβ) and tau measured on the fully automated Lumipulse platform with pre‐symptomatic Alzheimer's disease (AD) pathology on amyloid positron emission tomography (PET). METHODS: In 72 individuals from the Insight...

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Detalles Bibliográficos
Autores principales: Keshavan, Ashvini, Wellington, Henrietta, Chen, Zhongbo, Khatun, Ayesha, Chapman, Miles, Hart, Melanie, Cash, David M., Coath, William, Parker, Thomas D., Buchanan, Sarah M., Keuss, Sarah E., Harris, Matthew J., Murray‐Smith, Heidi, Heslegrave, Amanda, Fox, Nick C., Zetterberg, Henrik, Schott, Jonathan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Cerebrospinal Fluid Biomarkers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7503103/
https://www.ncbi.nlm.nih.gov/pubmed/32999915
http://dx.doi.org/10.1002/dad2.12097
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