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SARS-CoV-2 Pandemic Impacts on NASA Ground Operations to Protect ISS Astronauts

NASA implements required medical tests and clinical monitoring to ensure the health and safety of its astronauts. These measures include a pre-launch quarantine to mitigate the risk of infectious diseases. During space missions, most astronauts experience perturbations to their immune system that ma...

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Autores principales: Makedonas, George, Mehta, Satish K., Scheuring, Richard A., Haddon, Robert, Crucian, Brian E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7503132/
https://www.ncbi.nlm.nih.gov/pubmed/32971311
http://dx.doi.org/10.1016/j.jaip.2020.08.064
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author Makedonas, George
Mehta, Satish K.
Scheuring, Richard A.
Haddon, Robert
Crucian, Brian E.
author_facet Makedonas, George
Mehta, Satish K.
Scheuring, Richard A.
Haddon, Robert
Crucian, Brian E.
author_sort Makedonas, George
collection PubMed
description NASA implements required medical tests and clinical monitoring to ensure the health and safety of its astronauts. These measures include a pre-launch quarantine to mitigate the risk of infectious diseases. During space missions, most astronauts experience perturbations to their immune system that manifest as a detectable secondary immunodeficiency. On return to Earth, after the stress of re-entry and landing, astronauts would be most vulnerable to infectious disease. In April 2020, a crew returned from International Space Station to NASA Johnson Space Center in Houston, Texas, during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. Post-flight quarantine protocols (both crew and contacts) were enhanced to protect this crew from SARS-CoV-2. In addition, specific additional clinical monitoring was performed to determine post-flight immunocompetence. Given that coronavirus disease 2019 (COVID-19) prognosis is more severe for the immunocompromised, a countermeasures protocol for spaceflight suggested by an international team of scientists could benefit terrestrial patients with secondary immunodeficiency.
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spelling pubmed-75031322020-09-21 SARS-CoV-2 Pandemic Impacts on NASA Ground Operations to Protect ISS Astronauts Makedonas, George Mehta, Satish K. Scheuring, Richard A. Haddon, Robert Crucian, Brian E. J Allergy Clin Immunol Pract Rostrum NASA implements required medical tests and clinical monitoring to ensure the health and safety of its astronauts. These measures include a pre-launch quarantine to mitigate the risk of infectious diseases. During space missions, most astronauts experience perturbations to their immune system that manifest as a detectable secondary immunodeficiency. On return to Earth, after the stress of re-entry and landing, astronauts would be most vulnerable to infectious disease. In April 2020, a crew returned from International Space Station to NASA Johnson Space Center in Houston, Texas, during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. Post-flight quarantine protocols (both crew and contacts) were enhanced to protect this crew from SARS-CoV-2. In addition, specific additional clinical monitoring was performed to determine post-flight immunocompetence. Given that coronavirus disease 2019 (COVID-19) prognosis is more severe for the immunocompromised, a countermeasures protocol for spaceflight suggested by an international team of scientists could benefit terrestrial patients with secondary immunodeficiency. Elsevier Inc 2020 2020-09-21 /pmc/articles/PMC7503132/ /pubmed/32971311 http://dx.doi.org/10.1016/j.jaip.2020.08.064 Text en Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Rostrum
Makedonas, George
Mehta, Satish K.
Scheuring, Richard A.
Haddon, Robert
Crucian, Brian E.
SARS-CoV-2 Pandemic Impacts on NASA Ground Operations to Protect ISS Astronauts
title SARS-CoV-2 Pandemic Impacts on NASA Ground Operations to Protect ISS Astronauts
title_full SARS-CoV-2 Pandemic Impacts on NASA Ground Operations to Protect ISS Astronauts
title_fullStr SARS-CoV-2 Pandemic Impacts on NASA Ground Operations to Protect ISS Astronauts
title_full_unstemmed SARS-CoV-2 Pandemic Impacts on NASA Ground Operations to Protect ISS Astronauts
title_short SARS-CoV-2 Pandemic Impacts on NASA Ground Operations to Protect ISS Astronauts
title_sort sars-cov-2 pandemic impacts on nasa ground operations to protect iss astronauts
topic Rostrum
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7503132/
https://www.ncbi.nlm.nih.gov/pubmed/32971311
http://dx.doi.org/10.1016/j.jaip.2020.08.064
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