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Integrating Gene and Protein Expression Reveals Perturbed Functional Networks in Alzheimer’s Disease
Asymptomatic and symptomatic Alzheimer’s disease (AD) subjects may present with equivalent neuropathological burdens but have significantly different antemortem cognitive decline rates. Using the transcriptome as a proxy for functional state, we selected 414 expression profiles of symptomatic AD sub...
Autores principales: | Canchi, Saranya, Raao, Balaji, Masliah, Deborah, Rosenthal, Sara Brin, Sasik, Roman, Fisch, Kathleen M., De Jager, Philip L., Bennett, David A., Rissman, Robert A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7503200/ https://www.ncbi.nlm.nih.gov/pubmed/31340147 http://dx.doi.org/10.1016/j.celrep.2019.06.073 |
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