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TRPV1 Hyperfunction Involved in Uremic Toxin Indoxyl Sulfate-Mediated Renal Tubular Damage

Indoxyl sulfate (IS) is accumulated during severe renal insufficiency and known for its nephrotoxic properties. Transient receptor potential vanilloid 1 (TRPV1) is present in the kidney and acts as a renal sensor. However, the mechanism underlying IS-mediated renal tubular damage in view of TRPV1 is...

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Detalles Bibliográficos
Autores principales:	Lu, Chien-Lin, Liao, Chun-Hou, Lu, Kuo-Cheng, Ma, Ming-Chieh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7503230/ https://www.ncbi.nlm.nih.gov/pubmed/32867359 http://dx.doi.org/10.3390/ijms21176212

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