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The iRhom2/ADAM17 Axis Attenuates Bacterial Uptake by Phagocytes in a Cell Autonomous Manner
Uptake of bacteria by phagocytes is a crucial step in innate immune defence. Members of the disintegrin and metalloproteinase (ADAM) family critically control the immune response by limited proteolysis of surface expressed mediator molecules. Here, we investigated the significance of ADAM17 and its...
Autores principales: | Seifert, Anke, Wozniak, Justyna, Düsterhöft, Stefan, Kasparek, Petr, Sedlacek, Radislav, Dreschers, Stephan, Orlikowsky, Thorsten W., Yildiz, Daniela, Ludwig, Andreas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7503280/ https://www.ncbi.nlm.nih.gov/pubmed/32825187 http://dx.doi.org/10.3390/ijms21175978 |
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