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The iRhom2/ADAM17 Axis Attenuates Bacterial Uptake by Phagocytes in a Cell Autonomous Manner

Uptake of bacteria by phagocytes is a crucial step in innate immune defence. Members of the disintegrin and metalloproteinase (ADAM) family critically control the immune response by limited proteolysis of surface expressed mediator molecules. Here, we investigated the significance of ADAM17 and its...

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Detalles Bibliográficos
Autores principales: Seifert, Anke, Wozniak, Justyna, Düsterhöft, Stefan, Kasparek, Petr, Sedlacek, Radislav, Dreschers, Stephan, Orlikowsky, Thorsten W., Yildiz, Daniela, Ludwig, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7503280/
https://www.ncbi.nlm.nih.gov/pubmed/32825187
http://dx.doi.org/10.3390/ijms21175978

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