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The Role of the Kynurenine Signaling Pathway in Different Chronic Pain Conditions and Potential Use of Therapeutic Agents

Tryptophan (TRP) is an essential, aromatic amino acid catabolized by indoleamine 2,3-dioxygenase (IDO) and tryptophan 2,3-dioxygenase (TDO) enzymes into kynurenine. The IDO enzyme is expressed in peripheral tissues and the central nervous system. Another enzyme of interest in the kynurenine signalin...

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Detalles Bibliográficos
Autores principales:	Jovanovic, Filip, Candido, Kenneth D., Knezevic, Nebojsa Nick
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7503462/ https://www.ncbi.nlm.nih.gov/pubmed/32842609 http://dx.doi.org/10.3390/ijms21176045

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