Farnesoid X Receptor Activation Stimulates Organic Cations Transport in Human Renal Proximal Tubular Cells

Farnesoid X receptor (FXR) is a ligand-activated transcription factor highly expressed in the liver and kidneys. Activation of FXR decreases organic cation transporter (OCT) 1-mediated clearance of organic cation compounds in hepatocytes. The present study investigated FXR regulation of renal cleara...

Descripción completa

Detalles Bibliográficos
Autores principales: Wongwan, Teerasak, Chatsudthipong, Varanuj, Soodvilai, Sunhapas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7503471/
https://www.ncbi.nlm.nih.gov/pubmed/32846898
http://dx.doi.org/10.3390/ijms21176078

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7503471/
https://www.ncbi.nlm.nih.gov/pubmed/32846898
http://dx.doi.org/10.3390/ijms21176078

Ejemplares similares