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Farnesoid X Receptor Activation Stimulates Organic Cations Transport in Human Renal Proximal Tubular Cells

Farnesoid X receptor (FXR) is a ligand-activated transcription factor highly expressed in the liver and kidneys. Activation of FXR decreases organic cation transporter (OCT) 1-mediated clearance of organic cation compounds in hepatocytes. The present study investigated FXR regulation of renal cleara...

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Detalles Bibliográficos
Autores principales:	Wongwan, Teerasak, Chatsudthipong, Varanuj, Soodvilai, Sunhapas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7503471/ https://www.ncbi.nlm.nih.gov/pubmed/32846898 http://dx.doi.org/10.3390/ijms21176078

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