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Production of a Granulysin-Based, Tn-Targeted Cytolytic Immunotoxin Using Pulsed Electric Field Technology
Granulysin is a protein present in the granules of human cytotoxic T lymphocytes (CTL) and natural killer (NK) cells, with cytolytic activity against microbes and tumors. Previous work demonstrated the therapeutic effect of the intratumoral injection of recombinant granulysin and of the systemic inj...
Autores principales: | Guerrero-Ochoa, Patricia, Aguilar-Machado, Diederich, Ibáñez-Pérez, Raquel, Macías-León, Javier, Hurtado-Guerrero, Ramón, Raso, Javier, Anel, Alberto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7503585/ https://www.ncbi.nlm.nih.gov/pubmed/32859066 http://dx.doi.org/10.3390/ijms21176165 |
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