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Production of a Granulysin-Based, Tn-Targeted Cytolytic Immunotoxin Using Pulsed Electric Field Technology

Granulysin is a protein present in the granules of human cytotoxic T lymphocytes (CTL) and natural killer (NK) cells, with cytolytic activity against microbes and tumors. Previous work demonstrated the therapeutic effect of the intratumoral injection of recombinant granulysin and of the systemic inj...

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Detalles Bibliográficos
Autores principales: Guerrero-Ochoa, Patricia, Aguilar-Machado, Diederich, Ibáñez-Pérez, Raquel, Macías-León, Javier, Hurtado-Guerrero, Ramón, Raso, Javier, Anel, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7503585/
https://www.ncbi.nlm.nih.gov/pubmed/32859066
http://dx.doi.org/10.3390/ijms21176165

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