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Kyoto classification in patients who developed multiple gastric carcinomas after Helicobacter pylori eradication

BACKGROUND: Endoscopic Kyoto classification predicts gastric cancer risk; however, the score in the patients with primary gastric cancer after Helicobacter pylori (H. pylori) eradication therapy is unknown. AIM: To elucidate the Kyoto classification score in patients with both single gastric cancer...

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Autores principales: Sakitani, Kosuke, Nishizawa, Toshihiro, Toyoshima, Akira, Yoshida, Shuntaro, Matsuno, Tatsuya, Yamada, Tomoharu, Irokawa, Masatoshi, Takahashi, Yoshiyuki, Nakai, Yousuke, Toyoshima, Osamu, Koike, Kazuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7503616/
https://www.ncbi.nlm.nih.gov/pubmed/32994858
http://dx.doi.org/10.4253/wjge.v12.i9.276
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author Sakitani, Kosuke
Nishizawa, Toshihiro
Toyoshima, Akira
Yoshida, Shuntaro
Matsuno, Tatsuya
Yamada, Tomoharu
Irokawa, Masatoshi
Takahashi, Yoshiyuki
Nakai, Yousuke
Toyoshima, Osamu
Koike, Kazuhiko
author_facet Sakitani, Kosuke
Nishizawa, Toshihiro
Toyoshima, Akira
Yoshida, Shuntaro
Matsuno, Tatsuya
Yamada, Tomoharu
Irokawa, Masatoshi
Takahashi, Yoshiyuki
Nakai, Yousuke
Toyoshima, Osamu
Koike, Kazuhiko
author_sort Sakitani, Kosuke
collection PubMed
description BACKGROUND: Endoscopic Kyoto classification predicts gastric cancer risk; however, the score in the patients with primary gastric cancer after Helicobacter pylori (H. pylori) eradication therapy is unknown. AIM: To elucidate the Kyoto classification score in patients with both single gastric cancer and multiple gastric cancers developed after H. pylori eradication. METHODS: The endoscopist recorded the Kyoto classification at the endoscope and the Kyoto classification score at the time of the first diagnosis of gastric cancer after H. pylori eradication. The score was compared between single gastric cancer group and multiple gastric cancers group. RESULTS: The Kyoto score at the time of diagnosis of 45 cases of gastric cancer after H. pylori eradication was 4.0 points in average. The score was 3.8 points in the single gastric cancer group, and 5.1 points in the multiple gastric cancers group. The multiple group had a significantly higher score than the single group (P = 0.016). In the multiple gastric cancers group, all the patients (7/7) had 5 or higher Kyoto score, while in single gastric cancer group, the proportion of patients with a score of 5 or higher was less than half, or 44.7% (17/38). CONCLUSION: Patients diagnosed with gastric cancer after H. pylori eradication tended to have advanced gastritis. In particular, in cases of multiple gastric cancers developed after H. pylori eradication, the endoscopic Kyoto classification score tended to be 5 or higher in patients with an open type atrophic gastritis and the intestinal metaplasia extended to the corpus.
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spelling pubmed-75036162020-09-28 Kyoto classification in patients who developed multiple gastric carcinomas after Helicobacter pylori eradication Sakitani, Kosuke Nishizawa, Toshihiro Toyoshima, Akira Yoshida, Shuntaro Matsuno, Tatsuya Yamada, Tomoharu Irokawa, Masatoshi Takahashi, Yoshiyuki Nakai, Yousuke Toyoshima, Osamu Koike, Kazuhiko World J Gastrointest Endosc Retrospective Study BACKGROUND: Endoscopic Kyoto classification predicts gastric cancer risk; however, the score in the patients with primary gastric cancer after Helicobacter pylori (H. pylori) eradication therapy is unknown. AIM: To elucidate the Kyoto classification score in patients with both single gastric cancer and multiple gastric cancers developed after H. pylori eradication. METHODS: The endoscopist recorded the Kyoto classification at the endoscope and the Kyoto classification score at the time of the first diagnosis of gastric cancer after H. pylori eradication. The score was compared between single gastric cancer group and multiple gastric cancers group. RESULTS: The Kyoto score at the time of diagnosis of 45 cases of gastric cancer after H. pylori eradication was 4.0 points in average. The score was 3.8 points in the single gastric cancer group, and 5.1 points in the multiple gastric cancers group. The multiple group had a significantly higher score than the single group (P = 0.016). In the multiple gastric cancers group, all the patients (7/7) had 5 or higher Kyoto score, while in single gastric cancer group, the proportion of patients with a score of 5 or higher was less than half, or 44.7% (17/38). CONCLUSION: Patients diagnosed with gastric cancer after H. pylori eradication tended to have advanced gastritis. In particular, in cases of multiple gastric cancers developed after H. pylori eradication, the endoscopic Kyoto classification score tended to be 5 or higher in patients with an open type atrophic gastritis and the intestinal metaplasia extended to the corpus. Baishideng Publishing Group Inc 2020-09-16 2020-09-16 /pmc/articles/PMC7503616/ /pubmed/32994858 http://dx.doi.org/10.4253/wjge.v12.i9.276 Text en ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. http://creativecommons.org/licenses/by-nc/4.0/ This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.
spellingShingle Retrospective Study
Sakitani, Kosuke
Nishizawa, Toshihiro
Toyoshima, Akira
Yoshida, Shuntaro
Matsuno, Tatsuya
Yamada, Tomoharu
Irokawa, Masatoshi
Takahashi, Yoshiyuki
Nakai, Yousuke
Toyoshima, Osamu
Koike, Kazuhiko
Kyoto classification in patients who developed multiple gastric carcinomas after Helicobacter pylori eradication
title Kyoto classification in patients who developed multiple gastric carcinomas after Helicobacter pylori eradication
title_full Kyoto classification in patients who developed multiple gastric carcinomas after Helicobacter pylori eradication
title_fullStr Kyoto classification in patients who developed multiple gastric carcinomas after Helicobacter pylori eradication
title_full_unstemmed Kyoto classification in patients who developed multiple gastric carcinomas after Helicobacter pylori eradication
title_short Kyoto classification in patients who developed multiple gastric carcinomas after Helicobacter pylori eradication
title_sort kyoto classification in patients who developed multiple gastric carcinomas after helicobacter pylori eradication
topic Retrospective Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7503616/
https://www.ncbi.nlm.nih.gov/pubmed/32994858
http://dx.doi.org/10.4253/wjge.v12.i9.276
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