Biotech-Educated Platelets: Beyond Tissue Regeneration 2.0

The increasing discoveries regarding the biology and functions of platelets in the last decade undoubtedly show that these cells are one of the most biotechnological human cells. This review summarizes new advances in platelet biology, functions, and new concepts of biotech-educated platelets that c...

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Autores principales: Andrade, Sheila Siqueira, Faria, Alessandra Valéria de Sousa, Girão, Manoel João Batista C., Fuhler, Gwenny M., Peppelenbosch, Maikel P., Ferreira-Halder, Carmen V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7503652/
https://www.ncbi.nlm.nih.gov/pubmed/32842455
http://dx.doi.org/10.3390/ijms21176061
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author Andrade, Sheila Siqueira
Faria, Alessandra Valéria de Sousa
Girão, Manoel João Batista C.
Fuhler, Gwenny M.
Peppelenbosch, Maikel P.
Ferreira-Halder, Carmen V.
author_facet Andrade, Sheila Siqueira
Faria, Alessandra Valéria de Sousa
Girão, Manoel João Batista C.
Fuhler, Gwenny M.
Peppelenbosch, Maikel P.
Ferreira-Halder, Carmen V.
author_sort Andrade, Sheila Siqueira
collection PubMed
description The increasing discoveries regarding the biology and functions of platelets in the last decade undoubtedly show that these cells are one of the most biotechnological human cells. This review summarizes new advances in platelet biology, functions, and new concepts of biotech-educated platelets that connect advanced biomimetic science to platelet-based additive manufacturing for tissue regeneration. As highly responsive and secretory cells, platelets could be explored to develop solutions that alter injured microenvironments through platelet-based synthetic biomaterials with instructive extracellular cues for morphogenesis in tissue engineering beyond tissue regeneration 2.0.
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spelling pubmed-75036522020-09-27 Biotech-Educated Platelets: Beyond Tissue Regeneration 2.0 Andrade, Sheila Siqueira Faria, Alessandra Valéria de Sousa Girão, Manoel João Batista C. Fuhler, Gwenny M. Peppelenbosch, Maikel P. Ferreira-Halder, Carmen V. Int J Mol Sci Review The increasing discoveries regarding the biology and functions of platelets in the last decade undoubtedly show that these cells are one of the most biotechnological human cells. This review summarizes new advances in platelet biology, functions, and new concepts of biotech-educated platelets that connect advanced biomimetic science to platelet-based additive manufacturing for tissue regeneration. As highly responsive and secretory cells, platelets could be explored to develop solutions that alter injured microenvironments through platelet-based synthetic biomaterials with instructive extracellular cues for morphogenesis in tissue engineering beyond tissue regeneration 2.0. MDPI 2020-08-23 /pmc/articles/PMC7503652/ /pubmed/32842455 http://dx.doi.org/10.3390/ijms21176061 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Andrade, Sheila Siqueira
Faria, Alessandra Valéria de Sousa
Girão, Manoel João Batista C.
Fuhler, Gwenny M.
Peppelenbosch, Maikel P.
Ferreira-Halder, Carmen V.
Biotech-Educated Platelets: Beyond Tissue Regeneration 2.0
title Biotech-Educated Platelets: Beyond Tissue Regeneration 2.0
title_full Biotech-Educated Platelets: Beyond Tissue Regeneration 2.0
title_fullStr Biotech-Educated Platelets: Beyond Tissue Regeneration 2.0
title_full_unstemmed Biotech-Educated Platelets: Beyond Tissue Regeneration 2.0
title_short Biotech-Educated Platelets: Beyond Tissue Regeneration 2.0
title_sort biotech-educated platelets: beyond tissue regeneration 2.0
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7503652/
https://www.ncbi.nlm.nih.gov/pubmed/32842455
http://dx.doi.org/10.3390/ijms21176061
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