A Sphingosine 1-Phosphate Gradient Is Linked to the Cerebral Recruitment of T Helper and Regulatory T Helper Cells during Acute Ischemic Stroke

Emerging evidence suggests a complex relationship between sphingosine 1-phosphate (S1P) signaling and stroke. Here, we show the kinetics of S1P in the acute phase of ischemic stroke and highlight accompanying changes in immune cells and S1P receptors (S1P(R)). Using a C57BL/6 mouse model of middle c...

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Detalles Bibliográficos
Autores principales: Lucaciu, Alexandra, Kuhn, Hannah, Trautmann, Sandra, Ferreirós, Nerea, Steinmetz, Helmuth, Pfeilschifter, Josef, Brunkhorst, Robert, Pfeilschifter, Waltraud, Subburayalu, Julien, Vutukuri, Rajkumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7503682/
https://www.ncbi.nlm.nih.gov/pubmed/32872326
http://dx.doi.org/10.3390/ijms21176242

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