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Identification of Potential Chemical Substrates as Fuel for Hypoxic Tumors That May Be Linked to Invadopodium Formation in Hypoxia-Induced MDA-MB-231 Breast-Cancer Cell Line
Hypoxia plays a significant role in solid tumors by the increased expression of hypoxia-inducible factor-1α (HIF-1α), which is known to promote cancer invasion and metastasis. Cancer-cell invasion dynamically begins with the degradation of the extracellular matrix (ECM) via invadopodia formation. Th...
Autores principales: | Hamad, Hamad Ali, Enezei, Hamid Hammad, Alrawas, Anmar, Zakuan, Noraina Muhamad, Abdullah, Nurul Akmaryanti, Cheah, Yoke Kqueen, Hashim, Nur Fariesha Md |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7503683/ https://www.ncbi.nlm.nih.gov/pubmed/32858793 http://dx.doi.org/10.3390/molecules25173876 |
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