Cargando…

HP1γ Sensitizes Cervical Cancer Cells to Cisplatin through the Suppression of UBE2L3

Cisplatin is the most frequently used agent for chemotherapy against cervical cancer. However, recurrent use of cisplatin induces resistance, representing a major hurdle in the treatment of cervical cancer. Our previous study revealed that HP1γ suppresses UBE2L3, an E2 ubiquitin conjugating enzyme,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yi, Sang Ah, Kim, Go Woon, Yoo, Jung, Han, Jeung-Whan, Kwon, So Hee
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7503686/ https://www.ncbi.nlm.nih.gov/pubmed/32825184 http://dx.doi.org/10.3390/ijms21175976

Ejemplares similares

HPV-mediated nuclear export of HP1γ drives cervical tumorigenesis by downregulation of p53
por: Yi, Sang Ah, et al.
Publicado: (2020)

Suppression and recovery of BRCA1-mediated transcription by HP1γ via modulation of promoter occupancy
por: Choi, Jae Duk, et al.
Publicado: (2012)

Citrullination of HP1γ chromodomain affects association with chromatin
por: Wiese, Meike, et al.
Publicado: (2019)

The lncRNA UBE2R2-AS1 suppresses cervical cancer cell growth in vitro
por: Liu, Chunyan, et al.
Publicado: (2020)

Two Enhances the Cisplatin Sensitivity of Cervical Cancer Cells via Suppression of c-MET Expression
por: Chen, Ziqin, et al.
Publicado: (2023)

HP9800 - HP2401 interface
por: Littlewood, R K
Publicado: (1977)

Identification of a novel S6K1 inhibitor, rosmarinic acid methyl ester, for treating cisplatin-resistant cervical cancer
por: Nam, Ki Hong, et al.
Publicado: (2019)

Combination of ACY-241 and JQ1 Synergistically Suppresses Metastasis of HNSCC via Regulation of MMP-2 and MMP-9
por: Cho, Ha Young, et al.
Publicado: (2020)

Rosmarinic Acid Methyl Ester Regulates Ovarian Cancer Cell Migration and Reverses Cisplatin Resistance by Inhibiting the Expression of Forkhead Box M1
por: Lim, Soo Hyun, et al.
Publicado: (2020)

Expression and clinical significance of UBE2V1 in cervical cancer
por: Ren, Zhishuai, et al.
Publicado: (2021)

Interex HP1000/HP9000 Conference
Publicado: (1988)

HP certified: HP-UX system administration
por: Rehman, Rafeeq Ur
Publicado: (2000)

HP1γ function is required for male germ cell survival and spermatogenesis
por: Brown, Jeremy P, et al.
Publicado: (2010)

HP-1γ Controls High-Affinity Antibody Response to T-Dependent Antigens
por: Ha, Ngoc, et al.
Publicado: (2014)

Mechanisms Underlying the Regulation of HP1γ by the NGF-PKA Signaling Pathway
por: Seo, Seungmae, et al.
Publicado: (2018)

Heterochromatin Protein 1: A Multiplayer in Cancer Progression
por: Jeon, Yu Hyun, et al.
Publicado: (2022)

Platinum sensitivity and non-cross-resistance of cisplatin analogue with cisplatin in recurrent cervical cancer
por: Takekuma, Munetaka, et al.
Publicado: (2015)

UBE1a Suppresses Herpes Simplex Virus-1 Replication
por: Ikeda, Marina, et al.
Publicado: (2020)

TonEBP suppresses adipogenesis and insulin sensitivity by blocking epigenetic transition of PPARγ2
por: Ho Lee, Jun, et al.
Publicado: (2015)

The Bifunctional Enzyme SpoT Is Involved in the Clarithromycin Tolerance of Helicobacter pylori by Upregulating the Transporters HP0939, HP1017, HP0497, and HP0471
por: Geng, Xiwen, et al.
Publicado: (2017)

Role of the Epigenetic Regulator HP1γ in the Control of Embryonic Stem Cell Properties
por: Caillier, Maïa, et al.
Publicado: (2010)

Chromatin Regulation by HP1γ Contributes to Survival of 5-Azacytidine-Resistant Cells
por: Imanishi, Satoshi, et al.
Publicado: (2018)

Improvement of solubility and pharmacokinetic profile of hepatoprotector icariin through complexation with HP-γ-cyclodextrin
por: Ding, Yili, et al.
Publicado: (2023)

Interactome Analysis Reveals that Heterochromatin Protein 1γ (HP1γ) Is Associated with the DNA Damage Response Pathway
por: Kim, Hongtae, et al.
Publicado: (2016)

HP-UX 11i Version 2 system administration: HP integrity and HP 9000 servers
por: Poniatowski, Marty
Publicado: (2005)

Identification of Chromosomal HP0892-HP0893 Toxin-Antitoxin Proteins in Helicobacter pylori and Structural Elucidation of Their Protein-Protein Interaction
por: Han, Kyung-Doo, et al.
Publicado: (2013)

HP 9816
Publicado: (1982)

Contributions of UBE2C and UBE2S to meiotic progression of porcine oocytes
por: FUJIOKA, Yoshie A., et al.
Publicado: (2018)

Human germ cell tumours: expression of γ-glutamyl transpeptidase and sensitivity to cisplatin
por: Hanigan, M H, et al.
Publicado: (1999)

HP pavilion pcs made easy: the official HP guide
por: Stevenson, Nancy
Publicado: (2003)

AG490 and PF431396 Sensitive Tyrosine Kinase Control the Population Heterogeneity of Basal STAT1 Activity in Ube1l Deficient Cells
por: Now, Hesung, et al.
Publicado: (2016)

Knock-down of NDRG2 sensitizes cervical cancer Hela cells to cisplatin through suppressing Bcl-2 expression
por: Liu, Junye, et al.
Publicado: (2012)

Mechanism and disease association of E2-conjugating enzymes: lessons from UBE2T and UBE2L3
por: Alpi, Arno F., et al.
Publicado: (2016)

Nucleosome compaction facilitates HP1γ binding to methylated H3K9
por: Mishima, Yuichi, et al.
Publicado: (2015)

Deacetylation induced nuclear condensation of HP1γ promotes multiple myeloma drug resistance
por: Li, Xin, et al.
Publicado: (2023)

Enhancement of Cisplatin Sensitivity in Human Cervical Cancer: Epigallocatechin-3-Gallate
por: Kilic, Ulkan, et al.
Publicado: (2015)

NHERF1 Enhances Cisplatin Sensitivity in Human Cervical Cancer Cells
por: Tao, Tao, et al.
Publicado: (2017)

UBE2T promotes breast cancer tumor growth by suppressing DNA replication stress
por: Dutta, Roshan, et al.
Publicado: (2022)

Pentoxifylline sensitizes human cervical tumor cells to cisplatin-induced apoptosis by suppressing NF-kappa B and decreased cell senescence
por: Hernandez-Flores, Georgina, et al.
Publicado: (2011)

Epigenetic role of nuclear S6K1 in early adipogenesis
por: Yi, Sang Ah, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_d9ufn4vuvlf9hg5f4g4isjb2ul