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Blockade of Hemichannels Normalizes the Differentiation Fate of Myoblasts and Features of Skeletal Muscles from Dysferlin-Deficient Mice

Dysferlinopathies are muscle dystrophies caused by mutations in the gene encoding dysferlin, a relevant protein for membrane repair and trafficking. These diseases are untreatable, possibly due to the poor knowledge of relevant molecular targets. Previously, we have shown that human myofibers from p...

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Detalles Bibliográficos
Autores principales: Cea, Luis A., Fernández, Gabriela, Arias-Bravo, Guisselle, Castillo-Ruiz, Mario, Escamilla, Rosalba, Brañes, María C., Sáez, Juan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7503700/
https://www.ncbi.nlm.nih.gov/pubmed/32825681
http://dx.doi.org/10.3390/ijms21176025