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Dual Oxidase Maturation Factor 1 Positively Regulates RANKL-Induced Osteoclastogenesis via Activating Reactive Oxygen Species and TRAF6-Mediated Signaling

Receptor activator of NF-κB ligand (RANKL) induces generation of intracellular reactive oxygen species (ROS), which act as second messengers in RANKL-mediated osteoclastogenesis. Dual oxidase maturation factor 1 (Duoxa1) has been associated with the maturation of ROS-generating enzymes including dua...

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Detalles Bibliográficos
Autores principales: Cheon, Yoon-Hee, Lee, Chang Hoon, Jeong, Da Hye, Kwak, Sung Chul, Kim, Soojin, Lee, Myeung Su, Kim, Ju-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7503776/
https://www.ncbi.nlm.nih.gov/pubmed/32899248
http://dx.doi.org/10.3390/ijms21176416