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Effects of N-Substituents on the Functional Activities of Naltrindole Derivatives for the δ Opioid Receptor: Synthesis and Evaluation of Sulfonamide Derivatives

We have recently reported that N-alkyl and N-acyl naltrindole (NTI) derivatives showed activities for the δ opioid receptor (DOR) ranging widely from full inverse agonists to full agonists. We newly designed sulfonamide-type NTI derivatives in order to investigate the effects of the N-substituent on...

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Detalles Bibliográficos
Autores principales:	Iwamatsu, Chiharu, Hayakawa, Daichi, Kono, Tomomi, Honjo, Ayaka, Ishizaki, Saki, Hirayama, Shigeto, Gouda, Hiroaki, Fujii, Hideaki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7503831/ https://www.ncbi.nlm.nih.gov/pubmed/32825410 http://dx.doi.org/10.3390/molecules25173792

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